How It Works — From First Order to Month 6

How True Health Protocol works in practice — not in theory. This page is the operating manual for everything we sell. If you've never bought longevity supplements before, read this before you order. If you already have a routine, skip to Month 3+ for the layering logic.

The 60-second answer

• Pick a goal first, not a product. Cellular energy & longevity, beauty & skin, or metabolic health. Three different protocols, three different starting collections.
• Stacks beat singles. NAD+ precursors need sirtuin activators. Collagen needs Vitamin C. Resveratrol needs fat. Most actives stop being "nutraceuticals" and start being biology when they're paired correctly.
• Daily, with a meal, in the morning is the default for ~85% of our catalog. Sporadic dosing is the #1 reason longevity supplements feel like nothing.
• Don't expect Day-1 effects. NAD+ rises in 1–2 weeks, mitochondrial respiration shifts at 4–8 weeks, dermal collagen density at 8–12 weeks, bone-formation markers at 3–6 months. The molecules work on biology's timescale, not caffeine's.
• Layer, don't pile. Start with 1–2 actives. Add the next one at week 4–8 only if you've tracked something. Six supplements at once means you can't tell what's working.
• Backed by a 30-day satisfaction guarantee. See our guarantee page.

Step 1 — Find your primary goal

Every protocol starts with a single goal. The whole catalog is organized around three of them. Pick the one that matches what you actually want to change in the next 6 months — not a vague "feel better" — and the rest of the protocol follows.

Goal A — Cellular energy & longevity

You want the underlying biology of aging — mitochondrial output, NAD⁺ levels, sirtuin activity — to behave more like a 30-year-old's. Energy through the afternoon, exercise recovery, fewer "tired Mondays." This is the largest catalog vertical and the deepest research base. Start at Longevity Essentials or the NAD+ Family.

Goal B — Skin, hair, nails & visible aging

You want measurable changes in the mirror — fewer fine lines, more skin elasticity, stronger nails, less hair shedding, slower visible aging. Connective tissue and keratin biology is the lever. Start at Beauty & Anti-Aging or Skin Protocol.

Goal C — Metabolic health & glucose control

You want better fasting glucose, better insulin sensitivity, lipid panel improvements, less post-meal sluggishness, and the metabolic flexibility you had in your 20s. Start with Berberine HCL 500mg on the Metabolic collection page, and pair with Cardiovascular Longevity for full coverage.

Two more secondary goals you might layer on top of one of the three above:

• Cognitive longevity — sustained focus, memory, neuroprotection. See Brain & Cognitive Longevity.
• Fertility / reproductive longevity — egg quality, sperm parameters, hormonal foundations. See Fertility.

Not sure which one you are? Getting Started walks the decision based on age, current routine, and what you want to be different in 6 months. Or read Our Science for the López-Otín hallmarks-of-aging framework that organizes the whole catalog underneath.

Step 2 — Pick a stack, not a single product

Almost every longevity active works better paired than alone. This is not a marketing tactic — it's biochemistry. NAD⁺ is a substrate; sirtuins are the enzymes that use it. Without an activator, you're paying for the gas without the engine. Here are the four flagship pairings the catalog is built around.

Pairing 1 — NMN + Resveratrol (the Sinclair stack)

Longevity Stack Bundle — NMN 500mg + Resveratrol 600mg ($74.99). NMN is the substrate that becomes NAD⁺ via the salvage pathway (NMN → NAD⁺ via NMNAT1/2/3). Trans-resveratrol is the SIRT1 allosteric activator first identified by Howitz et al. (2003, Nature) and structurally validated by Hubbard et al. (2013, Science) as lowering the K_m of SIRT1 for its peptide substrate ~5×. You raise the substrate and the enzyme's appetite for it. Read the deep-dive on Pure NMN 500mg or step up to NMN 1000mg Double Strength.

Pairing 2 — Marine Collagen + Biotin + HA + Vitamin C (the skin stack)

Beauty & Longevity Stack ($74.99) covers four legs of the skin/hair/nail biology: peptides for substrate (Pro-Hyp/Hyp-Gly tripeptides per Iwai 2005 JAFC), keratin synthesis cofactor (Patel 2017 Skin Appendage Disord), dermal hydration via HA (Kawada 2014 Nutr J), and prolyl-4-hydroxylase activity for crosslink stability (the Vitamin C requirement; Pullar 2017 Nutrients). You can also build it à la carte from Marine Collagen 5000mg + Biotin 10,000mcg + HA + Vitamin C.

Pairing 3 — Berberine + Curcumin (the metabolic-inflammation stack)

Berberine HCL 500mg activates AMPK (the master metabolic sensor) through a mitochondrial-Complex-I-inhibition mechanism similar to metformin (Yin 2008 Metabolism; Cao 2019 meta-analysis). Curcumin 1000mg + BioPerine suppresses NF-κB-driven inflammation, which is the silent passenger in most metabolic dysfunction. The pair addresses both the energy-sensing problem and the chronic-low-grade-inflammation problem at once. The black-pepper piperine in the curcumin formula raises bioavailability ~20× per Shoba 1998 Planta Medica.

Pairing 4 — Senolytic burst (Quercetin + Fisetin, pulsed)

Senescent cells accumulate with age and secrete the senescence-associated secretory phenotype (SASP) — a cocktail of IL-6, IL-8, MMPs and growth factors that ages the surrounding tissue. The Mayo Clinic's 2018 Lancet EBioMedicine work used dasatinib + quercetin pulses; Fisetin 500mg is the over-the-counter analog (Yousefzadeh 2018 EBioMedicine ranked it the most potent of 10 flavonoids tested), and Quercetin 500mg is the cofactor. Run as a 2-3 day pulse once a month, not daily.

Bundles are priced lower than the sum of components ($13–18 saved). Read the full stacking guide for layered protocols beyond these four anchor stacks.

Step 3 — Your first dose

Three rules cover ~85% of the catalog. Specific exceptions are in the per-product pages and the table below.

Rule 1 — Take in the morning, with breakfast

NMN, NR, NAD⁺ precursors, Resveratrol, Pterostilbene, CoQ10, Berberine, Curcumin, Vitamin D3, Astaxanthin, Urolithin A — all benefit from morning dosing for two reasons. (a) Circadian-rhythm biology: SIRT1 activity, AMPK activity, and many of the metabolic switches longevity supplements pull on are highest during active hours. (b) Many of these molecules are fat-soluble (Vitamin D, K2, Resveratrol, Astaxanthin, Urolithin A, CoQ10, Curcumin) and absorb 2-7× better with dietary fat. A breakfast with eggs, avocado, nuts, or olive oil dramatically raises plasma levels.

Rule 2 — Daily, not sporadically

NAD⁺ tissue levels rise with consistent daily intake; they don't accumulate the way fat-soluble vitamins do. Skipping 2–3 days resets you to baseline. The clinical trials these dose recommendations come from are all daily-dosing trials. Five-days-a-week dosing gets you partial benefit at best. Set a phone reminder, put the bottle next to your coffee maker, build the habit before you build the stack.

Rule 3 — Don't expect Day-1 effects

Most longevity supplements work structurally over weeks. Day 1 should feel like nothing (the exception being adaptogens like Ashwagandha KSM-66 which can shift cortisol within hours). If you "feel something dramatic" on Day 1 from NMN or resveratrol, it's probably placebo or caffeine confound. Real cellular work (mitochondrial biogenesis, sirtuin signalling, collagen synthesis) takes 2–12 weeks to register subjectively.

Timing exceptions to know

Product-specific timing details are on each individual page. See the NMN timing guide and the FAQ for more.

Step 4 — Weeks 2 through 12: what to actually expect

This is the section most longevity-supplement buyers wish they'd read first. The timeline below is anchored to actual published trial endpoints, not vibes.

If you've made it 12 weeks at full dose with zero perceived benefit, talk to your physician about bloodwork. The most common reasons longevity supplements feel like nothing:

• Vitamin D deficiency. Below 30 ng/mL serum 25(OH)D, almost nothing else works well. Vitamin D3 5000 IU + K2 MK-7 fixes it.
• Iron-deficiency anemia. Common in menstruating women and vegans. Supplementing the rest doesn't fix the oxygen-carrying capacity gap.
• B12 deficiency. Common over 50 due to declining intrinsic factor; vegan/vegetarian; and on metformin or PPIs.
• Subclinical hypothyroidism. TSH above the upper-third of "normal range" can mask fatigue improvements.
• Sleep apnea. No supplement competes with CPAP-treated sleep architecture.
• Insufficient protein intake. Below ~1.2 g/kg/day, the substrate floor for collagen, muscle, and recovery is missing.

Step 5 — Month 3+: layer the protocol

After 12 weeks, you've earned data on what's working. This is when the protocol gets personal. Don't stack 6 things at once at the start — stack them now, when you can tell what each one is doing.

Plateauing on energy?

Add CoQ10 400mg for mitochondrial electron-transport-chain support — particularly if you take a statin (statins block CoQ10's shared synthesis pathway). Add PQQ 20mg if you want mitochondrial biogenesis (more mitochondria, not just better-working ones — Chowanadisai 2010 JBC). Add Urolithin A 500mg for mitophagy (recycling damaged mitochondria — Andreux 2019 Nature Metab; Liu 2022 JAMA Network Open). Each of these targets a different leg of the mitochondrial-renewal triangle.

Aiming for metabolic flexibility?

Add Berberine HCL to the morning stack. Read Berberine vs Metformin first — it's the closest natural-pharmaceutical analog we sell. Pair with Alpha-Lipoic Acid 600mg for additional glucose-disposal support and Taurine 1000mg for cardiometabolic foundations.

Aiming for stronger skin/hair effects?

Add Liposomal Vitamin C 1000mg for prolyl-4-hydroxylase cofactor support (without it, collagen triple helices don't crosslink properly — that's literally what scurvy is). Add Astaxanthin 12mg for membrane-spanning antioxidant defense and UV resilience (Tominaga 2012 Acta Biochim Pol). Add Glutathione 500mg for skin-tone evenness (Handog 2016 Int J Dermatol) and the antioxidant master substrate.

Crossed 50?

Move from NMN 500 to NMN 1000mg Double Strength — the age-related NAD⁺ drop is steeper after 50 (Massudi 2012 PLoS One showed ~50% NAD⁺ decline from age 30 to 60). Or layer in Liposomal NAD+ Ultimate 1000mg for direct NAD⁺ delivery rather than just precursor. Add Calcium Alpha-Ketoglutarate 1000mg for the epigenetic-clock work (Demidenko 2021).

Cognitive longevity in mind?

Add Omega-3 Fish Oil 2000mg as foundation (DHA is ~30% of brain phospholipid; modest but consistent cognition data). Add Creatine Monohydrate — the cognitive-creatine literature has matured remarkably (Rae 2003; Avgerinos 2018 systematic review). Add Pterostilbene 100mg for BBB-crossing polyphenol coverage.

Building a senolytic-burst protocol?

Run Fisetin 500mg + Quercetin 500mg as a monthly 2–3 day pulse (e.g., the first weekend of each month at 500–1000mg/day each, then off). Add Spermidine 10mg daily for autophagy support (Eisenberg 2016 Nat Med). Read the Senolytics collection for the full pulsed protocol.

Methylation-aware NAD+ stacks?

Anyone running NMN/NR ≥500mg long-term should consider methyl-donor support. The body methylates excess nicotinamide via NNMT, depleting SAMe pools over time. Add TMG 1000mg (Trimethylglycine) to replenish methyl donors, plus Magnesium Glycinate 400mg as the cofactor for ~300 enzymatic reactions including methyltransferases.

The full layered protocol by age cohort is in our After-40 supplement guide and in Protocols — Supplement Stacks by Goal.

Step 6 — Track what matters

You can't optimize a protocol you can't measure. The signals to actually track:

Subjective (free, daily, take 2 minutes)

• Energy 1–10 rated at 3pm (the post-lunch dip is the most sensitive subjective biomarker).
• Sleep quality 1–10 rated on waking. Or better — wear a ring or watch and track HRV, deep-sleep minutes, and resting heart rate.
• Mood / motivation 1–10 in the morning.
• Workout PRs. Strength, endurance, recovery. Hard data.

Objective (annual, ~$100–250 from your physician or LabCorp/Quest)

• Comprehensive metabolic panel (glucose, A1C, lipid panel including ApoB and Lp(a), fasting insulin, HOMA-IR).
• Inflammatory markers (hs-CRP, homocysteine).
• Hormones (TSH, free T3, free T4, total testosterone, SHBG; estradiol & progesterone if relevant).
• Foundational vitamins (25(OH)D, B12, ferritin, magnesium RBC).

Optional advanced markers

• Epigenetic-age clock (TruDiagnostic, MyDNAge, Elysium Index — biological vs. chronological age).
• Whole-blood NAD⁺ assay (Jinfiniti, others — useful if running serious NAD+ stacks).
• VO₂ max (cardio-respiratory fitness — single best longevity predictor in the literature).
• Grip strength + 5-rep sit-to-stand (sarcopenia screens).
• DEXA scan (body composition + bone density).

Step 7 — Stay the course (or stop with intent)

Two failure modes to avoid:

• Quitting at week 4 because "I don't feel anything yet." Most of the structural endpoints (collagen density, mitochondrial respiration, bone formation, epigenetic clock shift) take 8–24 weeks. The subjective lift comes earlier but isn't universal — see Step 4. If you've been consistent at full dose for 12 weeks and nothing has moved, then retest your protocol.
• Cycling on/off randomly. The trial dose-response curves these protocols are anchored to are continuous-dosing curves. Pulse-cycling is appropriate for senolytics (Fisetin/Quercetin, 2–3 day pulse monthly) and arguably acceptable for some adaptogens, but for substrate molecules (NMN, NR, NAD⁺, glycine, taurine, creatine), continuous is the trial-replicated protocol.

If you do want to stop something, taper rather than cold-stop where possible — particularly Berberine (let A1C settle), Ashwagandha (HPA-axis), and high-dose NAD⁺ precursors. You won't get a "withdrawal" exactly, but the protocol's effect will fade over 4–8 weeks and a slow taper helps you separate "this stopped working" from "I just stopped taking it."

Common mistakes

• Stacking 6 supplements at once on Day 1. You can't tell what's working. Layer in tiers, 4–8 weeks apart. Start with one bundle.
• Sporadic dosing. Weekend-only or "when I remember" dosing fails. Daily consistency is the lever, not the dose ceiling.
• Expecting Day-1 effects. Real cellular work takes weeks. Caffeine is a stimulant; longevity supplements are structural.
• Ignoring the foundations. Sleep, strength training, protein intake, Vitamin D, and not smoking do more than any supplement. Get those in place first. Supplements are the optimization layer; lifestyle is the foundation.
• Picking by single-active marketing instead of mechanism. "I'll just buy NMN" without the activator (resveratrol/pterostilbene) is leaving 60–70% of the bench effect on the table.
• Skipping the pairing co-factor. Collagen without Vitamin C. NMN without methyl donors past 6 months. Fat-soluble actives (D3, K2, Resveratrol, Astaxanthin, Urolithin A, CoQ10, Curcumin) without a fat-containing meal — you absorb 10–20% of what you swallow vs 70–80% with fat.
• Senolytics taken daily. They're pulsed, not chronic. The Mayo Clinic protocol is 2–3 days, then a month off.
• Ignoring drug interactions. Berberine + diabetes meds. Quercetin + cyclosporine. Curcumin + warfarin. NAC + nitroglycerin. Always cross-check with your physician if you take Rx medication.
• Counterfeit Amazon supply. NMN, fisetin, urolithin A, and resveratrol are the four most-counterfeited supplements on Amazon. The savings disappear if 0% of the active is in the capsule. Buy through brand-direct or reputable retailers with batch CoAs.
• Refrigeration neglect. NMN, NR, and liposomal phospholipid formulas store best at <25°C. The bathroom medicine cabinet is the single worst storage location (~95% relative humidity, temperature swings every shower). The kitchen pantry is fine; the fridge is better for NMN.

Where to start now (decision matrix)

FAQ — the questions we get most

How many supplements is too many?

For a beginner, 1–2 actives plus a foundation (Vit D, Omega-3) is plenty. Most people running a serious longevity protocol settle into 5–8 actives long-term. More than ~10 daily and you're in the territory of pill-fatigue, drug-interaction risk, and "I can't tell what's doing what." The right number is the one you'll actually take consistently for 12+ weeks.

Can I take everything together in one go?

Most morning actives stack fine in a single dose. The exceptions: minerals (calcium, iron, zinc) compete for absorption with each other and with some polyphenols (curcumin, urolithin A binds iron) — separate by 4 hours where possible. Levothyroxine and PPIs interact with many supplements — take Rx 30 min before food, and supplements 1–2 hours later.

Pre-workout, post-workout, or doesn't matter?

Doesn't matter for most actives. Two specific exceptions worth knowing: collagen + Vitamin C is most effective taken ~30 min pre-exercise (Shaw 2017 doubled collagen synthesis with this protocol). Antioxidants in high doses immediately around exercise may blunt some training adaptations (Ristow 2009 PNAS "Ristow window" — vitamin C 1000mg + vitamin E 400 IU around training reduced insulin-sensitivity gains). For most catalog items, take them with breakfast and don't overthink the workout window.

Are these vegan / vegetarian / kosher / halal?

Most of the catalog is vegan and uses HPMC plant capsules. Exceptions: Marine Collagen, Multi Collagen Complex/Powder, Biotin softgels (gelatin shell), Vitamin D3+K2 softgels (gelatin shell), Omega-3 (fish), Astaxanthin (algae but in fish-gelatin softgels). The rest — NMN, NR, Resveratrol, Pterostilbene, Berberine, Curcumin, Quercetin, Fisetin, Apigenin, Spermidine, Urolithin A, NAC, Glycine, Taurine, Creatine, CaAKG, TMG, Magnesium, Ashwagandha, Glutathione — is vegan. Read each product page's allergens block to confirm batch-level.

I'm pregnant / nursing — can I take this?

Most longevity actives have not been studied in pregnancy or lactation. Default to your obstetrician. Foundational nutrients (Vit D3, Omega-3) and some collagen products are commonly prescribed for prenatal use, but anything with a hormonal or pharmacological effect (Berberine, Resveratrol, Quercetin, Fisetin, Spermidine, NMN/NR, Ashwagandha) should be paused until after weaning unless your physician disagrees.

I'm on prescription medication — what should I check?

The most-asked interactions: warfarin (interacts with Vitamin K2, high-dose Vitamin E, omega-3, curcumin, garlic, ginger — INR shift risk); statins (Berberine and CoQ10 are the relevant pair — Berberine adds glucose/lipid effect; CoQ10 replaces what statins block); diabetes medications (Berberine, ALA, Cinnamon — additive hypoglycemic effect, may need dose adjustment); SSRIs (St. John's Wort interaction is the famous one — none of our products contain it; Ashwagandha caution warranted); chemotherapy (default: pause antioxidants during active chemo unless your oncologist clears it, since some chemo regimens depend on oxidative damage to tumor cells). Always cross-check with your prescribing physician.

How long until I see something?

See the timeline table in Step 4. Compressed answer: 1–2 weeks for "easier mornings" if it's going to come, 4–8 weeks for cosmetic markers and exercise recovery, 8–12 weeks for the structural endpoints (skin elasticity, mitochondrial respiration, muscle endurance), 3–6 months for bone, hair, and epigenetic shifts.

Why is dose X mg here when other brands sell Y mg?

We dose to the trial-replicated dose, not to whatever-fits-in-the-capsule. NMN 500 / NMN 1000, Resveratrol 600, Pterostilbene 100, Urolithin A 500, Glycine 1500, NAC 600, Berberine 500 (× 2–3/day if needed), Curcumin 1000, Spermidine 10, CaAKG 1000 — all anchored to specific human or pre-human trials. Some competitors hide low doses inside "proprietary blends" that don't disclose the per-active mg. We disclose everything; see Quality & Sourcing for the full standard.

What about side effects?

Most catalog items are well-tolerated. The most-reported mild side effects: Berberine (GI upset if taken without food — split into 2–3 doses); Curcumin (occasional GI looseness at high doses); NAC (rare H2S "sulfur breath" — try lower dose); Quercetin (insomnia if taken too late); Magnesium (loose stools — Magnesium Glycinate is the best-tolerated form, which is what we sell); Ashwagandha (rare GI upset; rare thyroid effects in susceptible people). Stop and talk to your physician if you notice anything beyond mild and transient.

Do you ship internationally? How long?

Yes — primarily US, with select international fulfillment. Standard shipping to the US is 3–7 business days; international 7–14 business days. Full details on our Shipping Policy page.

What if it doesn't work for me?

30-day satisfaction guarantee on every product, including opened bottles. Read the policy on our guarantee page and the refund policy. Send us an email at support@truehealthprotocol.health and we'll handle it.

Are you a pharmacy / can you prescribe?

No. We sell dietary supplements regulated under DSHEA in the United States. We don't make disease-treatment claims, and these statements have not been evaluated by the FDA. We can't prescribe, diagnose, or replace medical advice. We're a clean-formulation, third-party-tested supply for the supplement category — your physician is the right person for the medical decisions. See About for what we are and aren't.

Why True Health Protocol vs Amazon?

Three reasons: (a) per-batch HPLC and heavy-metals testing through ISO/IEC 17025 labs (Eurofins, NSF, Alkemist); (b) batch CoAs available on request — Amazon counterfeit risk on NMN, NR, fisetin, and urolithin A is real; (c) the catalog is built as a coherent stacking system — you're buying into a protocol, not a single SKU. Read Quality & Sourcing for the full QC standard and Ingredient Sourcing for where every active comes from.

Can I open the capsule and put it in a smoothie?

For most non-enteric, non-time-release HPMC capsules in the catalog, yes. Marine collagen, NAC, glycine, taurine, creatine, TMG, CaAKG, and magnesium glycinate all dissolve fine in water, smoothies, or yogurt. Exceptions where you should NOT open the capsule: enteric-coated formulas (e.g., enteric Glutathione — the coating exists to bypass stomach acid), softgels (Vitamin D3+K2, Astaxanthin, Biotin, Omega-3 — they're oils), and time-release formulas. When in doubt, capsule integrity is part of the dose-response.

I'm in my 60s/70s — is it too late?

It is not. The Igarashi 2022 NMN trial was in men 65+, the Liu 2022 urolithin A trial was in middle-aged adults targeting an older endpoint, the Sekhar GlyNAC trials are explicitly in older adults. The biology of the hallmarks-of-aging targets (NAD⁺, mitochondrial function, glutathione cycle, autophagy, senescent-cell load) responds at any adult age. Read After 40 — what changes and what to add.

I just want one thing — what's the single best supplement?

There isn't one. If we had to pick, the answer for most adults is: Vitamin D3 + K2 MK-7. Most adults are insufficient (<30 ng/mL), the disease-prevention literature is the deepest of any supplement, and downstream nothing else works as well in a deficient state. After D3+K2: Omega-3, then Magnesium, then your goal-specific stack from the decision matrix above.

The full catalog — at a glance

NAD+ & sirtuin actives

• Pure NMN 500mg — entry-tier daily β-NMN.
• NMN 1000mg Double Strength — clinical-trial-tier dose.
• Nicotinamide Riboside (NR) — patented NAD+ precursor with B-vitamin cofactors.
• Liposomal NAD+ Ultimate 1000mg — direct NAD+ in 10-active phospholipid carrier.
• NAD+ Daily Boost — direct NAD+ + trans-resveratrol pair.
• NAD+ 1000mg Pure Focus Formula — NR + Resveratrol + PQQ + Quercetin drink mix.
• NAD+ 5-in-1 Complete Mitochondrial Formula — NMN + CoQ10 + B-Complex + antioxidants.
• Liquid NAD+ Anti-Aging Drink — NR berry stick packs.
• Resveratrol 600mg — trans-resveratrol for SIRT1 activation.
• Pterostilbene 100mg — methoxylated SIRT1 activator with BBB crossing.
• Apigenin 50mg — CD38 inhibitor; preserves NAD+ pools.
• TMG 1000mg — methyl donor for long-term NMN/NR stacks.

Mitochondrial renewal

• CoQ10 400mg — electron-transport-chain support; statin-pair.
• PQQ 20mg — mitochondrial biogenesis activator.
• Urolithin A 500mg — mitophagy activator; PINK1/Parkin pathway.
• Alpha-Lipoic Acid 600mg — universal antioxidant + mitochondrial cofactor.
• Calcium Alpha-Ketoglutarate 1000mg — epigenetic-clock work.

Senolytics & autophagy

• Fisetin 500mg — Mayo-ranked top senolytic flavonoid.
• Quercetin 500mg — senolytic + natural antihistamine cofactor.
• Spermidine 10mg — autophagy induction; daily-chronic.

Skin, hair & collagen

• Marine Collagen Peptides 5000mg — fast-absorbing Type I.
• Multi Collagen Complex (5 types) — broad-spectrum capsule.
• Multi Collagen Peptides Powder — unflavored 1lb tub.
• Biotin 10,000mcg — keratin-synthesis cofactor.
• HA 200mg + Vitamin C — dermal hydration.
• Liposomal Vitamin C 1000mg — collagen-synthesis cofactor + antioxidant.
• Astaxanthin 12mg — UV-defense; membrane-spanning.
• Glutathione 500mg — master antioxidant; skin tone.

Antioxidants & foundations

• NAC 600mg — glutathione precursor; respiratory + liver.
• Glycine 1500mg — GlyNAC partner; slow-wave sleep.
• Curcumin 1000mg + BioPerine — NF-κB suppression.
• Vitamin D3 5000 IU + K2 MK-7 — bone, cardiovascular, immune.
• Omega-3 Fish Oil 2000mg — high EPA/DHA.
• Magnesium Glycinate 400mg — TRAACS bisglycinate; sleep + methylation.

Metabolic, cardio & foundational amino acids

• Berberine HCL 500mg — AMPK activator.
• Taurine 1000mg — cardiovascular + mitochondrial sulfur amino acid.
• Creatine Monohydrate — strength + cognitive longevity.
• Ashwagandha KSM-66 600mg — cortisol, sleep, HPA-axis.

Bundles

• Longevity Stack Bundle — NMN 500 + Resveratrol 600 ($74.99, saves ~$13).
• Beauty & Longevity Stack — Marine Collagen + Biotin + HA + Vitamin C ($74.99).

Reading list — keep going

• Getting Started — Where to Begin
• Protocols — Supplement Stacks by Goal
• Our Science — The Hallmarks Framework
• Quality & Sourcing
• Ingredient Sourcing
• FAQ
• About True Health Protocol
• Our 30-Day Guarantee
• How to Stack Longevity Supplements — Practical 2026 Protocol
• Best Time to Take NMN
• Berberine vs Metformin
• Longevity Supplements After 40
• Marine vs Bovine Collagen

Browse by collection

• Longevity Essentials
• NAD+ Family
• Mitochondrial Renewal
• Senolytics
• Foundational Health
• Antioxidants
• Cardiovascular Longevity
• Brain & Cognitive Longevity
• Metabolic
• Fertility
• Beauty & Anti-Aging
• Skin Protocol
• Collagen Supplements
• Most Popular
• All Products

Backed by our 30-day satisfaction guarantee. Questions? Contact us or email support@truehealthprotocol.health.

This article is for informational purposes only and is not medical advice. These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure, or prevent any disease. Consult your physician before starting any supplement, especially if you are pregnant, nursing, have a medical condition, or take prescription medication.