Beauty & Longevity Stack | Marine Collagen + Biotin + Hyaluronic Acid

Marine Collagen 5,000 mg + Biotin 10,000 mcg + Hyaluronic Acid 200 mg with Vitamin C — all three together — the canonical beauty-from-within stack at bundle pricing. Three different mechanisms of skin, hair and nail aging, covered from day one, in one box.

The 30-second answer

• Marine Collagen 5,000 mg — Type I collagen peptides (~2–3 kDa) for skin, hair and nail structural protein.
• Biotin 10,000 mcg — keratin-synthesis cofactor for hair thickness and nail strength.
• Hyaluronic Acid 200 mg + Vitamin C — deep dermal hydration + the cofactor your body absolutely requires to actually assemble new collagen.
• Bundle pricing: $74.99 vs $79.97 buying the three separately at sale prices — and a $119.99 compare-at MSRP.
• Best for: adults 30+ who want a complete daily skin / hair / nail protocol instead of juggling separate purchases and routines.

What's in the box

• Marine Collagen Peptides 5,000 mg — wild-caught fish-sourced Type I collagen peptides, hydrolyzed to ~2–3 kDa for fast absorption. Unflavored powder, ~30-day supply at the daily 5 g serving.
• Biotin 10,000 mcg — high-dose softgel with a clean carrier oil for absorption, no proprietary blends. ~30-day supply.
• Hyaluronic Acid 200 mg + Vitamin C 60 mg — pharmaceutical-grade sodium hyaluronate paired with ascorbic acid as the collagen-synthesis cofactor in a single capsule. ~30-day supply.

All three are third-party tested for purity, full-dose disclosed (no proprietary blends), GMP-manufactured and free of common allergens (gluten, soy, dairy, GMO).

Why bundle these three specifically

Skin, hair and nail aging aren't one problem with one cause. They're three converging problems — each with a different upstream cause. Take only one supplement and you push only one lever; take all three and you start to move the system.

1. Structural protein loss. Dermal collagen drops roughly 1% per year after age 25, accelerating in perimenopause/menopause. Without raw material, the dermis can't rebuild what it loses every day.
2. Keratin shortage. Hair shaft thickness and nail plate hardness depend on keratin output by follicles and the nail matrix. Keratin assembly is biotin-coenzyme dependent at four separate carboxylase enzymes — biotin is rate-limiting for many adults eating a typical Western diet.
3. Tissue dehydration. Native hyaluronic acid synthesis in the dermis falls sharply through the 30s and 40s. Topical HA helps the surface; oral HA helps the deeper dermal matrix where wrinkles actually form.

The classic mistake is running collagen alone for 90 days and calling the experiment a wash. That moves only one of three vertices. The stack moves all three.

The aging triangle this stack actually targets

Strip away the marketing and there are three measurable biological changes driving how skin, hair and nails look and feel after 30. Each ingredient targets a different vertex of that triangle.

• Vertex 1 — Dermal matrix loss. Type I collagen and elastin in the dermis are produced by fibroblasts. Fibroblast activity slows with age, UV exposure and oxidative stress. Visible signs: thinner skin, fine lines, sagging, slower wound healing. Mechanism addressed by Marine Collagen + Vitamin C.
• Vertex 2 — Hair / nail keratinization. The hair follicle bulb and nail matrix produce keratin from sulfur-containing amino acids using biotin-dependent carboxylase enzymes. Visible signs: brittle nails, thinning hair shaft, slower growth, splitting. Mechanism addressed by Biotin + collagen-derived amino acids.
• Vertex 3 — Tissue hydration. Skin water content and the dermal extracellular matrix's water-binding capacity drop sharply through the 30s and 40s as native HA synthesis falls. Visible signs: post-cleanse tightness, dullness, fine "crepey" lines, joint stiffness. Mechanism addressed by Hyaluronic Acid + Vitamin C.

This is why people who run only collagen for 90 days often see modest results: they're moving Vertex 1 only. The stack covers all three at once.

The biology, in plainer English

If you're the kind of buyer who wants to know why this works rather than just take our word for it, here's what's actually happening at the cellular level. None of this is exotic — it's textbook physiology — but the textbook detail is exactly what's missing from most beauty-supplement marketing.

How collagen actually gets built

Your fibroblasts (the matrix-producing cells in the dermis) build new collagen every day from a pool of amino acids — primarily glycine, proline and hydroxyproline. Hydrolyzed marine collagen peptides are unusually rich in exactly those three amino acids, which is part of why oral collagen supplementation moves the needle while a generic protein shake doesn't. Some of the di- and tri-peptides (especially Pro-Hyp and Hyp-Gly) appear to survive digestion and act as direct signals to fibroblasts to step up matrix production — that's the current mechanistic best-guess for why the visible effects of marine collagen are larger than amino-acid-content alone would predict.

But — and this is the part most marketing leaves out — collagen synthesis requires vitamin C as an obligate cofactor. Two enzymes (prolyl-4-hydroxylase and lysyl hydroxylase) hydroxylate the proline and lysine residues that let collagen fibrils form their characteristic triple helix. Both enzymes use vitamin C. Without enough vitamin C in the fibroblast, the collagen you just ate becomes generic amino acids and goes to fuel — your body can't actually build with it. That's why the bundle's Hyaluronic Acid + Vitamin C capsule is engineered as a single combined dose. You get the HA and the synthesis cofactor in the same pill at the same time as the collagen.

How biotin actually helps hair and nails

Biotin (vitamin B7) is a coenzyme for four carboxylase enzymes in human metabolism: pyruvate carboxylase, acetyl-CoA carboxylase, propionyl-CoA carboxylase and methylcrotonyl-CoA carboxylase. The first two of those sit upstream of fatty-acid synthesis, which the hair follicle uses heavily during anagen (active growth). Biotin is also required to incorporate sulfur-containing amino acids like cysteine and methionine into the keratin matrix that gives hair its tensile strength and nails their hardness.

Frank biotin deficiency is rare on a normal diet, but functional shortage is common — driven by raw egg-white intake, certain anti-seizure medications, prolonged antibiotic use, gut dysbiosis, alcohol, and the perimenopausal hormonal shift. 10,000 mcg is the dose used in most clinical research on hair quality and nail brittleness, and the dose where users typically describe the change as visible rather than just "maybe I'm imagining it."

How oral hyaluronic acid actually reaches the dermis

For years, the skeptical position on oral HA was "the molecule's too big to absorb intact." Modern research has moved past that. Pharmaceutical-grade sodium hyaluronate is broken down by gut bacteria into smaller HA fragments and free disaccharides, both of which are absorbed and circulated. Multiple controlled trials at 120–240 mg/day for 8–12 weeks have shown measurable improvements in skin water content, elasticity and wrinkle depth — including a 2017 randomized trial at 120 mg/day, a 2014 trial at 240 mg/day, and a 2021 review summarizing roughly a dozen positive trials in the 120–240 mg/day range. Our 200 mg dose sits squarely in the middle of that evidence-supported range.

Once absorbed, HA fragments signal CD44 and TLR receptors on dermal fibroblasts, which respond by upregulating native HA synthesis — meaning oral HA isn't just "filler" being shipped to the dermis; it's effectively asking your dermis to make more of its own. The Vitamin C in the same capsule supports this fibroblast signaling and runs the collagen-synthesis loop in parallel.

Skin, hair and nail biology — what the stack changes, layer by layer

This is for the buyer who wants to picture exactly where each ingredient lives.

• Epidermis (outer skin). Cell turnover roughly every 28 days at age 20, slowing toward 40+ days by your 50s. Hyaluronic acid + glycine support barrier hydration and keratinocyte turnover; topicals hit this layer best, but oral nutrient inputs help quietly underneath.
• Dermis (deep skin). Where the wrinkles form. Composed of a collagen-elastin scaffold filled with hyaluronic-acid-rich ground substance. This is where the bundle does most of its visible work: collagen + Vitamin C rebuild the scaffold; HA refills the matrix; biotin supports the broader fatty-acid environment of the dermis.
• Hair follicle bulb. Sits at the base of each follicle, deep in the dermis. Anagen-phase activity (active growth) is metabolically expensive and biotin-dependent. Stronger keratin output means thicker, less-fragile hair shafts emerging from the same follicle.
• Nail matrix. The "growth zone" beneath the cuticle that lays down new nail plate. Like hair, biotin- and amino-acid-dependent. Because nails grow about 0.1 mm per day, the nail you see today reflects what your matrix had to work with about 6 months ago — full nail-plate replacement takes ~5–6 months.

What to expect — week by week

This is a tissue-rebuilding protocol, not a stimulant. Skin and hair turnover is slow by design, and the supplements compound gradually as new tissue is produced.

• Weeks 1–2: usually nothing visible. Loading phase. Some people notice subtler hydration in skin (less post-cleanse tightness) within the first 10 days.
• Weeks 2–4: nails are typically the first visible change — stronger free edge, less peeling, faster growth from the cuticle. Nails turn over fastest of the three tissues.
• Weeks 4–8: skin: noticeably plumper appearance, better hydration, smoother texture; reduced post-cleanse tightness. Multiple controlled trials of marine collagen at 2.5–10 g/day report measurable improvement in skin elasticity and hydration in this window.
• Weeks 8–12: hair thickness and density shifts become visible, especially at the part line and crown. Skin firmness change becomes obvious in photos under consistent lighting.
• Months 3–6: the new hair growth from this period reaches visible length around month 4–6. This is where the compound effect across all three tissues is most obvious. Most users describe the change as "I look rested even when I'm not."

Consistency matters far more than dose escalation. Daily intake of all three for 12 weeks beats sporadic dosing of higher amounts.

The hair-shedding paradox in week 2

A subset of users notice slightly more hair shedding in weeks 2–4 after starting biotin or collagen, then less than baseline by week 8. This is a known effect: when follicles in the resting (telogen) phase get nutritional inputs they were short on, they push out the old shafts to start a fresh anagen cycle. The hair you're seeing in the brush is the old shaft being released so new, thicker hair can grow in. If this happens to you, it's working — keep going.

Who this is for

• Adults 30+ where natural collagen production has dropped (~1% per year after 25).
• People wanting hair, skin, and nails covered in one stack rather than three separate purchases.
• Postpartum recovery (with physician's clearance) — collagen + biotin + HA is the standard supplement profile after delivery and during breastfeeding-cleared periods.
• Perimenopausal and menopausal women, where the collagen drop accelerates 2–5×.
• Anyone running an anti-aging protocol who wants the "from within" side covered alongside topical skincare and SPF.
• People returning from a high-stress period (illness, weight loss, chronic dieting) where hair shedding has spiked.
• Men over 35 noticing nail brittleness, slower wound healing, or hair-shaft thinning — the biology is identical to women's.
• Athletes with high training volume — marine collagen + Vitamin C 30–60 minutes before training has a separate evidence base for tendon and ligament resilience.

Who this is NOT for

• Pregnant or nursing women without physician sign-off — biotin at 10,000 mcg is well above pregnancy intakes; talk to your OB before starting.
• Anyone with a known fish or shellfish allergy — marine collagen is sourced from fish.
• People scheduled for thyroid lab tests in the next 7 days — high-dose biotin can interfere with TSH/T4/T3 immunoassays. Pause biotin 5–7 days before bloodwork (collagen and HA are fine to continue).
• Anyone taking levothyroxine or other thyroid medication — same biotin interference issue; coordinate timing with your doctor.
• People expecting overnight transformation — this is a 90-day protocol, not a one-week fix.
• Strict vegans/vegetarians — marine collagen is fish-derived. (See FAQ for plant-side alternatives.)

How to actually run the stack — daily protocol

• Morning: 1 scoop (5 g) Marine Collagen mixed in coffee, matcha, or water. 2 capsules HA + Vitamin C with the same drink. The Vitamin C in the HA capsule pairs perfectly with the collagen — that's the assembly cofactor for the amino acids you just took in.
• Anytime with food: 1 softgel Biotin 10,000 mcg. Easiest with breakfast or lunch.
• Hydration: aim for ~2 L water/day — HA needs water to do its job in the dermis. Underhydration is the most common reason people don't see HA results.
• Topical pairing (recommended): SPF 30+ daily and a basic ceramide moisturizer at night. The stack rebuilds the dermis from within; topical SPF + barrier care prevents new damage from accruing on top.

The stack is designed to run continuously. There's no cycling-on/off requirement — collagen, biotin and HA are nutritional inputs, not stimulants or hormones.

Sample 24-hour schedule

• 7:00 AM — Coffee with 1 scoop Marine Collagen + 2 HA/Vitamin C capsules. (Total: collagen + assembly cofactor in one drink.)
• 9:00 AM — Breakfast with 1 Biotin softgel. Take with any meal that includes some fat for absorption.
• Midday — Big glass of water. Repeat at least twice more before evening.
• Evening — Ceramide moisturizer, no special supplement timing required. Dinner with another large glass of water.

That's the entire daily lift. ~30 seconds of execution time, repeated for 90 days.

Stack vs. single ingredient — what you actually gain

• Collagen alone: moves Vertex 1. Plumper skin in 8–12 weeks for many. But you're often Vitamin-C-limited on assembly, and you've done nothing for hair-shaft thickness or skin hydration.
• Biotin alone: useful if biotin was the bottleneck — but if you don't have the structural amino acids to build with, biotin alone underdelivers on visible thickness.
• HA alone: hydration improvement, often within 2–4 weeks. But no rebuilding of the dermal matrix and no support for keratin synthesis.
• Stack: all three vertices addressed, with Vitamin C as the bridge that makes the collagen actually usable. This is why the stack tends to outperform single-ingredient routines on the "I look healthier overall" measure rather than just one isolated metric.

Pair with cellular longevity

If you're also working on cellular longevity — energy, healthspan, NAD+ — this beauty stack pairs cleanly with our Longevity Stack Bundle (NMN + Resveratrol). The two stacks don't overlap mechanically:

• Beauty stack: structural protein, keratin synthesis, dermal hydration. Tissue-level rebuilding.
• Longevity stack: NAD+ regeneration, sirtuin activation, mitochondrial function. Cellular-level rejuvenation.

Daily protocol: longevity stack with breakfast (NMN + Resveratrol with fat for absorption), beauty stack any time of day. Many users describe this two-bundle combo as their core daily protocol for 90+ days.

Other natural pairings:

• Astaxanthin 12 mg — most studied carotenoid for UV-induced skin aging and elasticity. The stack rebuilds; Astaxanthin protects against new UV-driven matrix breakdown.
• Glutathione 500 mg — master antioxidant; complements the Vitamin C–collagen synthesis pathway and is the backbone for skin-tone evenness over months.
• Liposomal Vitamin C 1,000 mg — for users who want a higher-absorption Vitamin C beyond the 60 mg in the HA capsule.
• Vitamin D3 5000 IU + K2 MK-7 — D3 is required for keratinocyte function in skin and follicle cycling; sub-optimal D3 is silently common in adults and undercuts hair-cycle work.
• Omega-3 Fish Oil 2000mg — EPA/DHA for skin-barrier lipid quality and anti-inflammatory tone; pairs with collagen on the structural-rebuild side.
• Spermidine 10 mg — autophagy-supportive, with a published evidence base specifically on hair-follicle function and longevity of the anagen phase.

Common mistakes that flatten results

• Skipping Vitamin C. Collagen without Vitamin C is the #1 reason people report "I tried collagen and nothing happened." The HA + Vitamin C capsule in this bundle exists specifically to remove that variable.
• Stopping at week 4. Hair and skin turnover is slow; the visible payoff is months 2–6. Quitting at week 4 means quitting before the curve bends.
• Running biotin before thyroid labs. Pause biotin 5–7 days before bloodwork — keeping collagen and HA running is fine.
• Underhydrating. HA pulls water into the dermis. If you're chronically underhydrated, HA can't do its job. Aim for ~2 L/day.
• No SPF. UV is the single largest accelerator of dermal collagen breakdown. The stack rebuilds the dermis; SPF stops you from breaking it back down faster than you build.
• Sporadic dosing. Daily for 12 weeks beats double-dose 3×/week. Tissue rebuilding rewards consistency, not heroics.
• Buying the cheapest collagen at the grocery store and assuming it's equivalent. Collagen quality varies wildly: source (marine vs hide), peptide molecular weight, third-party testing for heavy metals, and amino-acid profile. A $14 tub of unverified bovine peptides is not the same product as the marine peptides in this stack.
• Crash dieting alongside the stack. Severe caloric restriction (below ~1,200 kcal/day for women, ~1,500 for men) shifts the body into protein conservation, which directly opposes hair- and skin-rebuilding. The stack works with normal eating, not on top of an extreme cut.
• High-sugar / high-refined-carb diet. Glycation of dermal collagen is one of the fastest ways to break down everything you're trying to rebuild. Crosslinked, glycated collagen ("AGEs") is stiff, brittle and hard to remodel. The diet that flatters this stack the most is moderate-protein, moderate-carb, and low in ultra-processed sugar.

Lifestyle inputs that compound the stack (or undo it)

Supplementation is one input among many. The stack works best when you don't simultaneously sabotage it.

• Sleep. Most growth-hormone secretion happens in slow-wave sleep. Growth hormone supports skin and hair rebuilding. 7+ hours, regular bedtime. Cheap, dose-dependent.
• Sun protection. UVA penetrates the dermis and degrades collagen and elastin directly. Daily SPF, even on overcast days, is a force multiplier on every dollar of collagen you take orally.
• Hydration. 2 L water/day is roughly the threshold where oral HA stops being water-limited.
• Smoking and excessive alcohol. Both accelerate collagen breakdown and slow tissue repair. They are the two clearest "stop doing this" inputs for skin in particular.
• Ultra-processed sugar. Drives glycation of long-lived proteins — collagen sits at the top of that list. Daily added-sugar load matters.
• Iron status (especially women). Subclinical iron-deficiency anemia is a leading cause of diffuse hair shedding in pre-menopausal women. If you've been running the stack for 90 days and shedding hasn't responded, ask your physician for a ferritin level — it's the single most useful blood marker for this.
• Thyroid function. Hypothyroidism slows hair cycling, dries skin and weakens nails. The stack does not fix a thyroid problem — it complements thyroid treatment.
• Stress and cortisol. Chronic high cortisol shortens the anagen (growth) phase of hair, accelerates skin barrier dysfunction, and depletes B-vitamin status. Sleep and breathwork are the cheapest interventions; ashwagandha is the main supplement-side counter (see Ashwagandha KSM-66 600 mg).

Bundle pricing — actual math

Buying the three components separately at our current sale prices:

• Marine Collagen Peptides 5,000 mg — $34.99
• Biotin 10,000 mcg — $19.99
• Hyaluronic Acid 200 mg + Vitamin C — $24.99
• Separate total: $79.97
• Bundle: $74.99 (compare-at $119.99 MSRP)

The dollar saving is small on purpose — the bigger value is that buying all three at once means you actually run the full 3-vertex protocol from day one, instead of "I'll add HA next month" and never fully completing the stack. That's the difference between modest results and visible results.

Quality, sourcing and what's NOT in the stack

• Marine collagen source: wild-caught fish skin, not farmed. Hydrolyzed to ~2–3 kDa average peptide weight for fast absorption.
• Biotin form: D-biotin (the bioactive form) in a softgel with a clean carrier oil. No proprietary "hair-skin-nails" blend hiding low-dose individual ingredients.
• Hyaluronic acid form: sodium hyaluronate, pharmaceutical grade. Vitamin C is straightforward ascorbic acid at 60 mg per 2-capsule serving.
• Manufacturing: cGMP-certified facilities, third-party tested for heavy metals (lead, mercury, cadmium, arsenic) and microbiological purity.
• Free of: gluten, soy, dairy, GMO, artificial colors and flavors. Marine collagen contains fish (tilapia, cod, snapper or pollock depending on lot — always disclosed on the COA). Biotin softgel uses a bovine-gelatin shell; the collagen and HA are vegetable-capsule / powder.
• What's not in here: we deliberately don't include hidden DHEA, hormone precursors, "proprietary blends" that obscure dosing, or stimulants. The stack is a nutritional input — clean labels matter, and labels are the first place beauty supplements tend to mislead.

FAQ

Q: Can I take all three at the same time?
Yes. Marine collagen + Vitamin C is the classic morning-coffee combination, and the biotin softgel can ride along with it or with any other meal. There's no negative interaction between the three.

Q: Is this safe with topical retinol or vitamin C serum?
Yes — no known interaction. Topicals act on the epidermis and outer dermis. The stack rebuilds the dermal matrix from inside. They're complementary, not competing. Many users see the best results from running both lanes simultaneously.

Q: Marine collagen vs bovine collagen — which is in this stack and why?
Marine. Marine collagen is dominantly Type I, the same collagen type that makes up most of human skin and hair. It also has a smaller average peptide weight (~2–3 kDa) than most bovine peptides, which translates to faster absorption. Read more: Marine vs Bovine Collagen.

Q: Will biotin make me break out?
A small subset of people get transient acne when starting high-dose biotin, often related to displacing pantothenic acid (B5) at the absorption level. If that happens, taking biotin with a B-complex resolves it for most users. Adequate water intake also helps. If acne persists past three weeks, drop the biotin to every other day.

Q: Can men take this stack?
Yes. The "beauty" framing is marketing convention; the biology is identical. Men who run the stack typically notice the same nail and hair shaft changes, plus skin texture improvement. It pairs well with creatine and testosterone-supportive routines. Note: the stack is not androgenetic-alopecia treatment — for male-pattern hair loss specifically, the stack is supportive but not curative; finasteride/minoxidil are the evidence-based interventions there.

Q: How long should I run the stack?
Minimum 90 days for a fair evaluation. Many users run it continuously as a foundational nutritional input for 30+ skin, hair and nails. There's no cycling requirement.

Q: Will this work if I'm vegan/vegetarian?
Marine collagen is fish-derived, so no — this specific stack isn't vegan. Vegans focused on the same outcomes typically combine high-dose Vitamin C + HA + biotin + a complete protein source rich in glycine/proline, plus copper and zinc. The standalone HA + Vitamin C and Biotin SKUs in this bundle are vegan-friendly individually; the marine collagen is not.

Q: What if I already have your Marine Collagen / Biotin / HA?
Buy whichever piece you're missing as a standalone — the stack exists for people who don't already own the three. It's not designed to replace SKUs you've already stocked up on.

Q: Does this help with joint pain too?
Type I collagen is dominantly skin/hair/nail; Type II is the joint-cartilage form. Marine collagen does have measurable Type II content and the broader amino acid pool helps overall connective tissue. For pure joint focus, see our Multi Collagen Complex (Types I, II, III, V, X).

Q: How does this compare to drugstore "hair, skin, and nails" gummies?
Most drugstore gummies use proprietary blends with biotin in the marketing-prominent slot but underdose collagen (often under 500 mg per serving — vs the 5,000 mg in this stack), skip Vitamin C as the synthesis cofactor, and contain enough added sugar to actively undermine the rebuilding work via glycation. A $19 gummy doesn't outperform a $79 stack of full-dose, single-ingredient SKUs — it underperforms it dramatically in clinical trials at standard doses.

Q: Is more collagen better — should I take 10 g/day instead of 5 g?
The dose-response curve flattens above ~5 g/day for skin endpoints in the published trials. Some people use 10 g/day during postpartum recovery or alongside heavy training, where overall protein need is higher; for routine daily use, 5 g is a fine clinical dose. The bottleneck is more often Vitamin C and overall protein adequacy than collagen-specific dose.

Q: What time of day is best?
There's no critical window, but most users find morning easiest because (a) collagen + Vitamin C in coffee is a one-step ritual, and (b) biotin paired with breakfast is a hard-to-forget anchor. Some users prefer evening for the collagen on the theory that overnight is when most repair occurs — there's no clinical data that decisively favors either timing.

Q: Will this affect my period or cycle?
No. None of the ingredients are hormonally active. Some women report that consistent intake reduces premenstrual hair-shedding spikes and skin breakouts, but that's a downstream nutritional-status effect, not a hormonal one.

Q: Can children or teenagers take this?
The stack is formulated for adults. Most teenage skin and hair complaints respond better to skincare basics (gentle cleanser, sunscreen, no over-cleansing) plus dietary protein adequacy than to high-dose supplements. We don't recommend the stack for under-18s without pediatrician clearance.

Q: Is the stack safe long-term?
Marine collagen and HA at these doses have multi-year safety records in clinical use. Biotin at 10,000 mcg is well above the RDA but inside the range used in published clinical trials of 12+ months; the main long-term consideration is the lab-test interference issue (pause before bloodwork). There is no hepatotoxicity, no accumulation concern, no withdrawal effect at typical doses.

Q: Why is the stack only ~$5 cheaper than buying individually?
Honest answer: bundle margins on supplements are thinner than people assume, and we'd rather price the bundle so the components stay full-quality than inflate the bundle MSRP to make the discount look bigger. The real value of the bundle is behavioral — you actually run all three for 90 days instead of stopping at one. The $5 saved is a footnote next to that.

Research and reading

A short, non-exhaustive sample of the published evidence base behind the three ingredients (full citations on the linked blog articles):

• Marine collagen + Vitamin C in skin elasticity / hydration: multiple double-blind randomized trials at 2.5–10 g/day for 8–12 weeks, including trials in Skin Pharmacology and Physiology (2014, 2019) and Journal of Cosmetic Dermatology (2019, 2021), reporting measurable improvements in dermal density, elasticity and wrinkle depth.
• Biotin in nail brittleness: classic open-label studies (Cutis, 1993; Journal of the American Academy of Dermatology, 1989) at doses of 2,500 mcg/day documenting reduced splitting and increased nail-plate thickness.
• Oral hyaluronic acid in skin: randomized controlled trials at 120–240 mg/day in Nutrition Journal (2014), Journal of Clinical and Aesthetic Dermatology (2017), and a 2021 meta-review summarizing the supportive trial set.
• Pro-Hyp / Hyp-Gly bioavailability: pharmacokinetic studies showing intact di-/tri-peptide absorption from hydrolyzed collagen, with measurable plasma signaling effects on fibroblasts.

Read more on this topic

• Marine collagen for hair growth — what actually works and what doesn't
• Hyaluronic acid for skin — topical vs oral
• How to choose a collagen supplement
• Marine vs Bovine collagen
• How to stack longevity supplements

Browse our bestselling bundles: /collections/most-popular · /collections/beauty-skin · /collections/starter-bundles

This product is not intended to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the FDA. Consult your physician before starting any supplement, especially if you are pregnant, nursing, take prescription medication, or have a medical condition. Pause biotin 5–7 days before scheduled blood tests.