Quality & Sourcing

Most supplement companies hide behind "proprietary blends" and certifications nobody can verify. This page lays out, in plain language, exactly how True Health Protocol products are made, tested, labeled, sourced, and stored — and what each of those words actually means when you're deciding whether to put something in your body every day for the next decade.

If you only have a minute, the short version is in the box right below. If you want the long version with the laboratory acronyms decoded, the industry shortcuts named, the named manufacturing partners listed, and the per-batch CoA request flow spelled out — keep scrolling. Every section here exists because there is a way the supplement industry routinely cuts the corner, and we want you to recognize it the next time you read a label that isn't ours.

The 60-second answer

• Full milligram doses on every active. No proprietary blends, no "complex matrix" wording, no hidden sub-doses. The number on the label is the number in the capsule.
• Every batch tested by an ISO/IEC 17025-accredited third-party lab — not the manufacturer's own QC bench — for active-ingredient identity, potency, heavy metals, microbial contamination, and (where relevant) pesticide residue and residual solvents.
• cGMP manufacturing in FDA-registered, FDA-inspected facilities in the United States and the European Union, working with named partners (Selerb, Ixoreal Biomed for KSM-66, Sabinsa for BioPerine, Albion/Balchem for TRAACS bisglycinate). Partner names appear on the relevant product pages.
• Per-batch certificates of analysis (CoAs) on request. Email support@truehealthprotocol.health with your batch code (printed on the bottle) and we send the actual lab PDF for that bottle within one business day.
• Bioavailable form, not just any form. β-NMN (not α-NMN), trans-resveratrol (not cis), trans-pterostilbene, MK-7 menaquinone (not MK-4), magnesium bisglycinate (not oxide), TG-form omega-3 (not ethyl ester), reduced-glutathione (not oxidized) — every product page calls out the form by name.
• Country-of-origin transparency. Every active ingredient's source country is documented on the Ingredient Sourcing page; a condensed table appears below.
• Cal Prop 65 ICP-MS heavy-metal limits enforced. Lead ≤ 0.5 µg/day, mercury ≤ 0.3 µg/day inorganic / 0.7 µg/day methyl, cadmium ≤ 4.1 µg/day, inorganic arsenic ≤ 10 µg/day. Every batch CoA shows the actual measured ppm/ppb numbers, not just a "pass" stamp.
• If we wouldn't take it ourselves at the dose printed on the label, we don't sell it. That's the bar — and that's why our 30-day keep-the-bottle guarantee exists.

On this page

1. The 60-second answer
2. What's on every label, every time
3. Third-party testing — what actually gets tested, and how
4. The three-tier verification standard, in operational detail
5. cGMP manufacturing — what the certificate actually requires
6. How to read a Certificate of Analysis (CoA)
7. How to request a per-batch CoA — the email flow
8. Named manufacturing partners and trial-grade raw materials
9. Country-of-origin transparency table
10. Why we don't use proprietary blends
11. Form matters — the bioavailable-form checklist
12. Sourcing, by ingredient family
13. Capsules, excipients, and bottle materials
14. What's not in our products
15. Storage and stability — practical guidance
16. How to verify your specific batch
17. Industry shortcuts to recognize on other labels
18. What we're still working on
19. FAQ — quality and sourcing
20. Selected primary references
21. How we revise this page
22. Related pages

What's on every label, every time

• Full milligram doses for every active ingredient. No "proprietary blends." No "complex matrix" wording that hides individual amounts. If a label says 500 mg of Berberine HCl, it's 500 mg of Berberine HCl — not 500 mg of "metabolic complex" with 50 mg of berberine inside it. This is the single most predictive marker of supplement quality, and it is the easiest one for a consumer to verify with their own eyes.
• Source disclosure for every collagen and animal-derived product. Marine collagen is wild-caught fish; bovine collagen is grass-fed and pasture-raised; eggshell-membrane products are sustainably sourced from US egg producers. We name the source rather than letting you guess from the front-panel illustration.
• Third-party batch testing. Every batch is tested by an independent ISO/IEC 17025-accredited laboratory — not the manufacturer's lab — for active-ingredient identity, potency, contaminants, and (where relevant) microbial safety. The CoA travels with the batch and is available to you on request.
• Excipients and capsule materials. Vegetarian HPMC capsules where the active is shelf-stable in capsule form. Bovine gelatin softgels only where lipid-based actives — fish oil, vitamin D3, vitamin K2 MK-7, astaxanthin — require a softgel format for stability. Bottles are opaque amber HDPE with a foil induction seal and a desiccant for moisture control.
• Best-by and batch-code printing. Every bottle carries a printed batch number and best-by date. The batch number is what unlocks your CoA on request — keep it visible if you plan to ask.
• Form name on the front panel. The form of the active is printed where you can see it: "β-NMN," "trans-resveratrol," "MK-7 menaquinone," "TRAACS magnesium bisglycinate." If the form matters (and for these molecules it absolutely does), the form has to be visible without flipping the bottle.
• Country-of-origin disclosure on the supplement-facts panel or — for actives whose origin matters most — on the front panel. KSM-66 (India, Ixoreal Biomed), BioPerine (India, Sabinsa), TRAACS bisglycinate (USA, Albion/Balchem), Spermidine wheat-germ extract (Europe), Marine collagen (wild-caught Atlantic).
• FDA disclaimer footer on every label. "These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease." This is required by law and we print it at full readable size — not in a font you need a magnifier to find.

Third-party testing — what actually gets tested, and how

"Third-party tested" is one of the most overused phrases in the supplement industry. It is printed on bottles that have only been tested for one variable, on bottles tested by labs owned by the same parent company as the manufacturer, and even on bottles where the testing was a one-time event for a single batch from years ago. None of that is what testing should mean. Here's what we mean by it.

The five tests every batch goes through

1. Active-ingredient identity — high-performance liquid chromatography (HPLC), liquid chromatography–mass spectrometry (LC-MS), gas chromatography–mass spectrometry (GC-MS), or nuclear magnetic resonance (NMR) depending on the molecule. Confirms the molecule in the bottle is the molecule on the label. This is how you separate β-NMN (active) from α-NMN (a manufacturing isomer with much lower bioactivity), or trans-resveratrol (active) from cis-resveratrol (largely inactive). For plant extracts, identity testing also confirms the species — important for Berberine, where unrelated alkaloid sources occasionally turn up in cheaper supply chains, and for Curcumin, where unrelated dye-grade turmeric oleoresin is sometimes substituted into the supply.
2. Active-ingredient potency — assay, typically HPLC with a reference standard. Quantifies milligrams per capsule against the label claim. We accept the FDA-permitted ±10% as the pharma-industry tolerance, and most batches come in tighter than that. The CoA shows the actual measured value (e.g., "503.4 mg per capsule" against a 500 mg label claim) rather than just a "pass" stamp.
3. Heavy metals (ICP-MS, inductively coupled plasma–mass spectrometry). Lead, arsenic, cadmium, and mercury — the "big four" required by California Proposition 65 and best practice everywhere. Every batch is tested against the strictest of (USP <232>, ICH Q3D for elemental impurities, Prop 65 Safe Harbor) limits, and the CoA shows the actual ppm/ppb numbers, not a pass/fail flag. The Prop 65 Safe Harbor daily-exposure limits we enforce: lead ≤ 0.5 µg/day, inorganic mercury ≤ 0.3 µg/day, methyl mercury ≤ 0.7 µg/day, cadmium ≤ 4.1 µg/day, inorganic arsenic ≤ 10 µg/day. These are stricter than the USP <232> oral PDE limits and are why we test against the Prop 65 ceiling specifically.
4. Microbial contamination (USP <2021> / <2022>). Total aerobic plate count (TAMC), total yeast and mold count (TYMC), and absence of pathogens — Salmonella, E. coli, Staphylococcus aureus, and Pseudomonas aeruginosa. Especially relevant for raw-ingredient and powder products (Multi-Collagen Peptides Powder, Creatine, Marine Collagen Peptides, Glycine), where surface area and water activity create more opportunity for microbial growth. CFU/g limits are documented per USP chapter; the CoA shows the actual measured values.
5. Pesticide and residual-solvent residue (LC-MS / GC-MS multi-residue panels for pesticides; GC-headspace for residual solvents). All plant-extract actives — Resveratrol (Polygonum cuspidatum), Pterostilbene (Pterocarpus marsupium), Quercetin (Sophora japonica), Apigenin (chamomile or parsley extract), Curcumin (Curcuma longa), Spermidine (wheat germ), Berberine (Berberis aristata or Coptis chinensis), Urolithin A (precursor: pomegranate ellagitannins) — are tested against EU MRL (Maximum Residue Limit) panels covering 200+ pesticides, plus glyphosate-specific testing for any Chinese-supply-chain extracts. Residual solvents are tested per USP <467> for Class 1 (avoid: benzene, carbon tetrachloride), Class 2 (limit: methanol, hexane, acetonitrile), and Class 3 (low-toxicity: ethanol, acetone) classes.

What "independent" actually means

An "independent" lab in our supply chain has four properties: (1) ISO/IEC 17025 accreditation for the specific test methods used, (2) no corporate-ownership tie to the contract manufacturer doing the production, (3) a written method validation record that we can request, and (4) a unique CoA per batch with the lab's letterhead, lab signatory, and date — not a generic certificate that's reused across batches.

Here are the labs in our supply chain, by category: Eurofins Scientific (USA and Europe — heavy metals, microbial, pesticides) and SGS (USA and Europe — heavy metals, microbial, residual solvents) for routine batch QC; Alkemist Labs (California — botanical identity, including DNA barcoding for plant species verification); NOW Foods Quality Lab (where the partner manufacturer is NOW or its subsidiaries) for redundant identity confirmation; and partner-specific labs for trial-grade raw materials (e.g., the Mayo AFFIRM-spec fisetin batch carries lab documentation to its source-of-record).

The three-tier verification standard, in operational detail

Our CoA workflow rests on three tiers of verification. A batch only ships when all three pass.

Tier 1: Identity and potency at the contract-manufacturer level

Before a batch is encapsulated, the contract manufacturer's own QC bench runs identity and potency on the incoming raw materials. This is in-house testing — fast, low-stakes, designed to catch obviously-wrong material at the loading dock. A failed identity check at this stage means the raw material is rejected before it goes into the blend.

Identity methods used at this tier: HPLC for small-molecule actives (NMN, NR, Resveratrol, Pterostilbene, Quercetin, Apigenin, Berberine, Urolithin A, Fisetin, Spermidine, Curcumin); LC-MS for trace molecules; NMR for ambiguous-isomer cases (β-NMN vs α-NMN, trans-resveratrol vs cis); HPLC-UV for chromogenic actives (Astaxanthin, Vitamin K2 MK-7); ICP-OES (optical emission, less sensitive than ICP-MS but adequate for incoming-material screening) for mineral actives (Magnesium, Zinc when present in formulations, the iron in Multi-Collagen Powder).

Tier 2: Independent third-party laboratory verification

After encapsulation but before release-to-warehouse, the finished-good batch is sent to an ISO/IEC 17025-accredited third-party lab — Eurofins, SGS, Alkemist, or equivalent. The lab runs the full five-test panel (identity, potency, heavy metals, microbial, pesticides/residual solvents). The lab's CoA is signed by an authorized signatory, dated, and tied to a unique batch lot number. The lab does not see our internal QC numbers — they run the panel cold against the label claim.

The lab's CoA is the document we send you on request. It is the operational truth about your bottle.

Tier 3: Lot-release review and quarantine before shipping

Before any batch leaves the warehouse, our QC reviewer compares Tier 1 numbers against Tier 2 numbers. If they agree (within method precision), the batch passes lot release. If they disagree, the batch is quarantined and a deviation investigation opens — which, in practice, means the batch does not ship until the discrepancy is reconciled. In rare cases (we have had two in catalog history) a batch is rejected at this stage and re-manufactured.

This three-tier workflow is the operational reason our 30-day keep-the-bottle guarantee can credibly carry the language "keep the bottle" — by the time a bottle reaches you, three independent checkpoints have signed off on what's in it.

cGMP manufacturing — what the certificate actually requires

"cGMP" stands for "current Good Manufacturing Practice" and is the FDA's regulatory standard for dietary supplement manufacturing under 21 CFR Part 111. It is a real legal standard with FDA inspection authority — but it is also a credential that companies sometimes invoke loosely. Here's what the certificate actually means in our supply chain.

The 21 CFR Part 111 elements that govern our manufacturing

• Personnel. Trained, competent personnel, documented training records, exclusion of personnel with active illness from production areas.
• Physical plant and grounds. Separation of clean and dirty zones, controlled-air HVAC with HEPA filtration in encapsulation rooms, dedicated washdown zones for allergen-cross-contact prevention.
• Equipment. Documented cleaning and sanitization procedures, master cleaning logs, calibration records for analytical equipment (balances, HPLC, ICP-MS).
• Components, packaging, and labels. Incoming-material QC (Tier 1 above), supplier qualification records, label-reconciliation procedures so batch-coded labels match their batches.
• Production and process controls. Master manufacturing records, batch records that capture every operator action, in-process checks during encapsulation (capsule weight uniformity, blend homogeneity).
• Holding and distribution. Temperature- and humidity-controlled warehousing, FIFO (first-in-first-out) inventory rotation, sealed-pallet shipping records.
• Returned dietary supplements. Quarantine and disposition of returned product — returned bottles are never reintroduced to inventory.
• Product complaints. Documented complaint-handling, including any adverse-event reporting under Title 21 USC §379aa-1.
• Records and recordkeeping. All batch records retained for at least one year past the labeled best-by date, available to FDA on inspection.

FDA-registered, FDA-inspected — what each phrase means

FDA-registered means the facility has filed Form FDA 3537 establishing itself as a domestic or foreign establishment that manufactures, processes, packs, or holds food (and dietary supplements). Registration is mandatory under the Bioterrorism Act of 2002. It is necessary but not sufficient — registration alone is paperwork.

FDA-inspected means the facility has been physically inspected by the FDA under 21 CFR Part 111 since the most recent registration cycle. Inspection cadence is risk-based and typically every 2–5 years for dietary supplement facilities. Our partner facilities have inspection histories on record (FDA's FOIA-accessible 483 Form / Establishment Inspection Reports, where applicable). We do not work with facilities that have outstanding 483 observations unaddressed at the time of contract.

Geography of our manufacturing footprint

The contract-manufacturing locations split, roughly, between the United States (the majority of capsule and softgel actives) and the European Union (selected actives where the EU supply chain is the longer-established one — wheat-germ Spermidine, polyphenol-grade Apigenin extracts, certain TG-form Omega-3 batches). Both regulatory regimes require equivalent cGMP standards; the difference is jurisdictional, not quality-tier.

How to read a Certificate of Analysis (CoA)

A CoA is a one- to three-page lab document that — when it's a real one — tells you exactly what's in the bottle in front of you. Here's how to read one when we send it to you, and how to spot a fake one when somebody else sends one.

The fields a real CoA has

• Lab letterhead and accreditation number. ISO/IEC 17025 accreditation number from a recognized accrediting body (A2LA in the US, UKAS in the UK, DAkkS in Germany, etc.). The accreditation number is verifiable on the accrediting body's public registry.
• Sample identifier and batch lot number. The batch lot has to match the printed batch on your bottle. If a CoA's batch number is generic ("L20231" or just "Sample 1"), the document is not tied to your specific bottle and is not what you want.
• Date of receipt and date of analysis. Both should be present, typically within 10–14 days of each other for a normal turnaround. If the analysis is dated more than a year before the manufacture date, the CoA is probably from a different batch.
• Method reference. "USP <232> ICP-MS, lead by EPA Method 200.8" or equivalent — a real CoA cites the analytical method used. A vague "in-house method" without a method ID is a yellow flag.
• Specification, result, and units. For each parameter: the specification (what's allowed), the actual result, and the unit (mg/capsule, ppm, ppb, CFU/g). A real CoA shows numbers, not just "PASS / FAIL." This is the single most important diagnostic for whether a CoA is real or theatrical.
• Authorized signatory and date. A named individual who certifies the result, with a date. Many real CoAs are now electronically signed; the signature should be tied to a named lab employee, not to a company logo.

What a fake or theatrical CoA looks like

• No batch lot number, or a generic one that doesn't match the bottle.
• "Pass / fail" results without numerical values.
• No method references — just a list of parameters and a check mark.
• The lab's letterhead is a logo of the manufacturer rather than an accredited third-party lab.
• A single CoA reused across many batches (you can sometimes see the date is identical across multiple bottles).
• The accreditation number is missing or unverifiable.
• The CoA has only an active-ingredient potency line — no heavy-metal, microbial, or pesticide testing — and is presented as if it were comprehensive.

What our CoAs look like, specifically

Our CoAs are 1–3 pages, typically PDF. Page 1 is the cover summary: batch lot, date, methods, lab signatory, accreditation. Page 2 is the parameter table: each test row shows specification, result, units, method reference. Page 3, when present, is supporting chromatography data — HPLC chromatograms, ICP-MS calibration data, microbial plate-count tables. We send the lab's original PDF, unmodified, with no logos added or removed.

How to request a per-batch CoA — the email flow

Every batch of every product has a CoA on file. We don't post all of them publicly because — bluntly — most customers don't want to read 80+ PDFs, and posting them would create a maintenance burden that competes with actually shipping products. Instead, we send the specific CoA for the specific bottle in your hand, on request.

The four-field email

Send an email to support@truehealthprotocol.health with these four pieces of information:

1. Product name — the title from the front of the bottle (e.g., "NMN 1000mg Double Strength").
2. Batch lot number — printed on the bottom or back panel of the bottle, typically a 5–8-character alphanumeric code (e.g., "L23-A0431").
3. Best-by date — printed near the batch number; helps us disambiguate if there have been multiple batches with similar lot codes.
4. Order number (optional) — your True Health Protocol order number, which lets us cross-check that the CoA you receive matches the bottle we shipped you.

Turnaround and what you get back

One business day, typically faster. You will receive: (a) the original lab PDF of the CoA, unmodified; (b) a one-paragraph plain-English summary of what's on the CoA, in case you don't want to parse the chromatography sections; (c) a link to the relevant product page so you can cross-reference the label claims; and (d) an offer to answer any specific question about the numbers — e.g., "what is the actual lead level in this batch?" or "is the potency on the high side or the low side of the ±10% tolerance?"

What if you don't have the bottle in hand yet?

If you're researching before you order and want to see a representative CoA, just ask — we'll send one of the more recent batch CoAs for the product you're interested in. (It won't be your specific bottle's CoA, because the bottle hasn't shipped yet, but it will be a real CoA from a real recent batch.) Once you order and have the bottle in hand, you can request the specific CoA for your batch.

What if you've already taken the supplement?

We still send the CoA — even if the bottle is empty. Many customers request a CoA after a few weeks of taking a product because they want to confirm what was in the bottle they took. The CoA is tied to the batch, not to whether the bottle is full.

What we do not do

We do not redact CoAs, modify CoAs, or send "summary" CoAs that hide the underlying numbers. The lab PDF is the lab PDF. If a result is on the higher end of a Prop 65 limit (still passing — the limits are conservative), we don't hide that — we explain what it means and why the batch still passes the standard. Honesty about the numbers is the only credible way to operate this workflow long-term.

Named manufacturing partners and trial-grade raw materials

The supplement industry's worst habit is anonymous sourcing — labels that say "premium NMN" without telling you who actually makes it. Our better customers ask, and the answer should be on record. Here are the named partners behind the actives in our catalog. Each named partner is also disclosed on the relevant product page so the link between catalog and supply chain is visible end to end.

Named partners — branded raw-material suppliers

• Selerb — Brazil/India operations. Co-formulator and contract manufacturer for our NAD+ 5-in-1 Complete Mitochondrial Formula, which combines NMN, CoQ10, B-Complex, Trans-Resveratrol, and Pterostilbene in a single capsule. Selerb's role is disclosed on the product page; the formulation, doses, and stability profile come from Selerb's published spec.
• Ixoreal Biomed (India) — KSM-66 ashwagandha extract. The KSM-66 spec is the most-published ashwagandha extract in the clinical literature: ≥5% withanolides by HPLC, full-spectrum root extract (no leaf material), 14-day green-chemistry process. Trials referenced on our KSM-66 Ashwagandha 600mg page include Chandrasekhar 2012 (Indian J Psychol Med, n=64, 27.9% cortisol reduction) and Salve 2019 (Cureus, n=60, sleep + perceived-stress endpoints).
• Sabinsa (India) — BioPerine standardized piperine extract. 95% piperine from black-pepper fruit. The reference trial is Shoba 1998 (Planta Medica, n=8 healthy volunteers): 20 mg piperine increased serum curcumin AUC by 2,000% vs. curcumin alone. BioPerine appears in our Curcumin 1000mg + BioPerine and Apigenin 50mg + BioPerine products.
• Albion Minerals / Balchem (USA) — TRAACS magnesium bisglycinate chelate. Patented bisglycinate-chelate process producing a fully-reacted Mg-glycine-glycine chelate verified by FTIR spectroscopy. This is the form behind our Magnesium Glycinate 400mg TRAACS, which is methylation-supportive (the glycine is also a precursor for the glutathione-cycle and for GlyNAC's pairing with NAC).
• Creapure-spec micronized creatine (Germany / AlzChem). The Creapure spec is the highest-purity creatine monohydrate spec in the world (≥99.95% pure, no creatinine or dicyandiamide impurities). Our Creatine Monohydrate 1000mg uses Creapure-spec material.
• Polygonum cuspidatum (Japanese knotweed) trans-resveratrol — selected suppliers in China and Europe. Identity-verified ≥98% trans-resveratrol by HPLC, isomerization tested. Used in our Resveratrol 600mg and NMN 500 + Resveratrol 600 Longevity Stack.
• β-NMN (nicotinamide mononucleotide) — selected pharma-grade suppliers in China. Identity-verified by HPLC and NMR (β-anomer specifically — α-anomer is the manufacturing impurity to watch for, and the β/α ratio shows on every batch CoA). Used in our NMN 1000mg Double Strength, Pure NMN 500mg, and stack products. Yamaguchi 2022 (Endocr J, n=31, 12-week safety study) and Yoshino 2021 (Science, n=25, mechanistic study in postmenopausal women) are the human-trial reference points.

Trial-grade raw materials — actives whose source matches a published clinical trial

• Fisetin (Mayo AFFIRM-spec). The 500 mg dose used in our Fisetin 500mg matches the dosing arm in the Mayo Clinic AFFIRM trials (NCT03675724 and NCT04210986). The reference paper is Yousefzadeh 2018 (EBioMedicine, mouse model establishing fisetin as the most-effective senolytic among 10 flavonoids screened).
• Urolithin A (mitopure-grade). The 500 mg dose in our Urolithin A 500mg matches the dose in the Andreux 2019 trial (Nat Metab, n=60, 4-week mitochondrial-function study) and is consistent with the higher-dose arm of the Singh 2022 AMAZ-02 trial.
• Calcium α-ketoglutarate (CaAKG). Used in our Calcium Alpha-Ketoglutarate 1000mg; the reference points are Asadi Shahmirzadi 2020 (Cell Metab, mouse healthspan trial) and the TruDiagnostic 2021 case-series (8-year reversal of biological age on methylation-clock readouts after 7-month CaAKG protocol).
• Trans-pterostilbene (≥98% by HPLC, trans-isomer specifically). Used in our Pterostilbene 100mg; isomer matters because pterostilbene is the dimethylated analog of resveratrol with markedly higher oral bioavailability — the cis-isomer's pharmacology is largely unstudied and assumed inactive.
• NR (nicotinamide riboside, ChromaDex Niagen-spec material in selected products). Used in our Nicotinamide Riboside Hard Capsules and Liquid NAD+ Anti-Aging Drink; the patented Niagen material is the form used in Trammell 2016 (Nat Comm, n=12, NAD+ pharmacokinetics) and Martens 2018 (Nat Comm, n=24, blood-pressure endpoints).
• Spermidine wheat-germ extract (≥1.5 mg/g spermidine, EU supply chain). Used in our Spermidine 10mg Wheat Germ; the reference trial is the Eisenberg 2016 (Nat Med) cardiac-aging mouse model and the Schroeder 2021 SmartAge cognitive-aging human trial.
• TG-form Omega-3 (re-esterified triglyceride, not ethyl ester). Used in our Omega-3 Fish Oil 2000mg; the form-bioavailability trial is Dyerberg 2010 (Prostaglandins Leukot Essent Fatty Acids), which showed re-esterified TG outperformed ethyl-ester forms by ~70% on EPA+DHA serum AUC.
• D3 + K2 MK-7 (menaquinone-7, all-trans, ≥99% trans-isomer). Used in our Vitamin D3 5000 IU + K2 MK-7 100mcg; the reference trial is Knapen 2015 (Thromb Haemost, n=244, 3-year arterial-stiffness reduction) for K2 MK-7 specifically.

What "named" buys you, in practice

Named partners create supply-chain accountability. If a batch fails identity testing, we know whose lot it is. If a customer asks "is this the same KSM-66 used in Chandrasekhar 2012," the answer is yes (same manufacturer, same chemistry spec, same withanolide ≥5% standardization). If a competing brand uses an unnamed "ashwagandha extract" — that question cannot be answered, because the link to the trial supply chain is broken.

Country-of-origin transparency table

This is the condensed version of the country-of-origin table on the Ingredient Sourcing page. It shows, for every active in the catalog, where the active is sourced and the principal supply-chain note. The full per-ingredient deep-dive (including patent-grade reference, isomer specification, and selected-supplier rationale) lives on the Ingredient Sourcing page.

The full per-active sourcing detail — patent-grade reference, isomer notes, supplier-selection rationale, three-tier verification record — lives on Ingredient Sourcing, with the framework rationale on Our Science.

Why we don't use proprietary blends

A "proprietary blend" is a label-disclosure category permitted by FDA dietary-supplement labeling rules (21 CFR 101.36): the manufacturer lists the total weight of the blend and the names of its ingredients, but is not required to disclose the individual ingredient amounts. The intent of the rule was to protect formulation trade secrets. The reality, in practice, is that proprietary blends are most often used to mask under-dosing of the headline active so the label can list it without disclosing how little is there.

The under-dose pattern, in plain numbers

Take a hypothetical "Memory Support Blend, 800 mg" containing Bacopa monnieri, Lion's Mane, Gotu Kola, Ginkgo, Rhodiola, and Apigenin. The label is permitted to list these six ingredients in descending order by weight, with the total 800 mg. What the label is not required to disclose: that 750 of the 800 mg is bacopa (the cheapest of the six), and the apigenin is 5 mg — about 10% of any clinically-meaningful dose. The customer reads "Apigenin" and assumes a real dose; the formulation has only the wave of it.

How we side-step the trick

Every active in our catalog has its own line on the supplement-facts panel with its own milligram amount. Combination products (NAD+ 5-in-1, Beauty Stack, Longevity Stack Bundle) still itemize each active by name and dose, even where the marketing benefit of a single blend-name would be commercially convenient. Examples:

• The NAD+ 5-in-1 Complete Mitochondrial Formula lists NMN, CoQ10, B-Complex (B1, B2, B3, B5, B6, B12, biotin, folate), Trans-Resveratrol, and Pterostilbene with each of their individual milligram amounts on the supplement-facts panel.
• The Beauty & Longevity Stack lists Marine Collagen (5 g), Biotin (10,000 mcg), and Hyaluronic Acid (200 mg) individually — not as "Beauty Blend, 5,210 mg."
• The NMN 500 + Resveratrol 600 Longevity Stack ships as two separate bottles with two separate labels — full milligram doses on each.
• The NAD+ 1000mg Pure Focus Formula lists NR, Trans-Resveratrol, PQQ, and Quercetin individually with their milligram amounts; the 1000mg in the title refers to the NR-equivalent NAD+ precursor load, not a hidden blend total.

The exception that proves the rule

The only place a "blend" name appears on our labels is for B-complex sub-fractions where the FDA-recognized %DV (percent Daily Value) is the operationally-meaningful number — e.g., the B-vitamin sub-panel inside the NAD+ 5-in-1 still itemizes B1 / B2 / B3 / B5 / B6 / B12 / biotin / folate by individual %DV, but they are visually grouped on the panel under "B-Complex (vitamins)" because the customer reads %DV for B-vitamins, not absolute milligrams. This is a label-readability convention, not a dose-hiding device.

Form matters — the bioavailable-form checklist

For some molecules, the form of the active determines whether you absorb anything at all. Here is the form-by-form checklist for the actives in our catalog where this matters most.

Forms we use, and why

• NMN: β-anomer (β-NMN), not α-anomer. The β-anomer is the bioactive form; α is a manufacturing impurity. β/α ratio reported on every CoA. Used in NMN 1000mg and Pure NMN 500mg.
• Resveratrol: trans-resveratrol, not cis-resveratrol. The trans-isomer is the SIRT1-activating form referenced in Howitz 2003 and the rest of the resveratrol mechanism literature. Used in Resveratrol 600mg.
• Pterostilbene: trans-pterostilbene, not cis-pterostilbene. The trans-isomer is the dimethylated analog of trans-resveratrol with markedly higher oral bioavailability. Used in Pterostilbene 100mg.
• Astaxanthin: trans-astaxanthin from Haematococcus pluvialis microalgae, not synthetic astaxanthin. Synthetic astaxanthin uses different stereoisomer ratios (3S,3'S vs the 3R,3'R found in microalgae) and the natural form has the better antioxidant track record. Used in Astaxanthin 12mg.
• Vitamin K2: MK-7 (menaquinone-7), not MK-4. MK-7 has a 72-hour serum half-life vs. MK-4's 1–2 hour half-life — clinically meaningful for the once-daily dosing pattern. Knapen 2015 used MK-7 specifically. Used in D3 + K2 MK-7.
• Vitamin D3: cholecalciferol, not D2 (ergocalciferol). D3 raises serum 25(OH)D more reliably and is the form referenced in the VITAL trial (Manson 2019). Lanolin-derived (vegetarian); used in D3 + K2 MK-7.
• Magnesium: bisglycinate (TRAACS-spec chelate), not oxide. Mg-oxide is poorly absorbed and is the form behind the "magnesium-causes-loose-stools" reputation. TRAACS bisglycinate has higher absorption and less GI disturbance — and the glycine carrier supports glutathione-cycle and methylation pathways. Used in Magnesium Glycinate 400mg.
• Omega-3: re-esterified TG (triglyceride) form, not ethyl ester. TG-form has ~70% higher EPA+DHA serum AUC vs ethyl ester per Dyerberg 2010. Used in Omega-3 Fish Oil 2000mg.
• Glutathione: reduced (GSH) form, enteric-coated. The reduced form is the bioactive antioxidant form; enteric coating protects from gastric acid degradation. Used in Glutathione 500mg.
• NAC: pharma-grade N-acetyl-L-cysteine. The L-isomer specifically; D-NAC is biologically inert. Used in NAC 600mg and as the cysteine half of the GlyNAC pair (with Glycine 1500mg).
• Curcumin: 95% curcuminoids + BioPerine. Curcumin alone has very poor oral bioavailability; piperine (BioPerine) increases curcumin AUC by 2,000% per Shoba 1998. Used in Curcumin 1000mg + BioPerine.
• CoQ10: ubiquinone, not ubiquinol. Ubiquinone is the more chemically-stable form; the body reduces it to ubiquinol enzymatically. Q-SYMBIO used ubiquinone. Used in CoQ10 400mg.
• Creatine: creatine monohydrate, micronized, Creapure-spec. Creatine monohydrate has the deepest evidence base (Forbes 2022 meta-analysis); other forms (creatine HCl, creatine ethyl ester, kre-alkalyn) have not outperformed monohydrate in head-to-head trials. Used in Creatine 1000mg.
• Berberine: berberine HCl, not berberine sulfate. The HCl salt is the form used in the Yin 2008 and Lan 2015 meta-analysis trials. Used in Berberine HCl 500mg.
• Spermidine: wheat-germ extract standardized to ≥1.5 mg/g spermidine, not synthetic spermidine. The wheat-germ extract is what was used in the human trials (Eisenberg 2016 Nat Med, Schroeder 2021 SmartAge). Used in Spermidine 10mg.
• Hyaluronic acid: low-molecular-weight (≤120 kDa) for oral absorption. High-MW HA (≥500 kDa) is poorly absorbed orally; the Oe 2017 trial used low-MW HA specifically. Used in HA + Vitamin C.
• Marine collagen: hydrolyzed peptides, MW ≤3 kDa. Hydrolysis to small peptides is what allows oral absorption and skin / joint integration; full-length collagen would be digested to amino acids. Proksch 2014 used hydrolyzed peptides specifically. Used in Marine Collagen 5000mg.

Sourcing, by ingredient family

This is the catalog organized by ingredient family rather than by product, with the family-level sourcing rationale. The product-level detail is on each product page; the deeper per-ingredient detail is on Ingredient Sourcing.

NAD+ precursors — NMN, NR, Niacinamide

NMN (β-nicotinamide mononucleotide) is the upstream precursor most commonly used in the recent NAD+ literature (Yoshino 2021, Yamaguchi 2022, Igarashi 2022, Pencina 2023). NR (nicotinamide riboside) is the alternate precursor with the deepest pharmacokinetic record (Trammell 2016, Martens 2018, Brakedal 2022 NADPARK). Both raise NAD+ in human serum / muscle / brain tissue; the choice between them is partly preference, partly stability profile, partly cost. We carry both — NMN in 1000mg Double Strength and Pure NMN 500mg, NR in Nicotinamide Riboside Hard Capsules and Liquid NAD+ Anti-Aging Drink, plus NAD+-direct in Liposomal NAD+ Ultimate 1000mg — and let customers stack NAD+ precursor + sirtuin activator + methyl donor as needed. Browse the full NAD+ Family collection or the NMN sub-collection.

Sirtuin activators / SIRT1 family — Resveratrol, Pterostilbene

Resveratrol is the original SIRT1 activator (Howitz 2003 Nature; Hubbard 2013 Trends Pharm Sci); trans-resveratrol from Polygonum cuspidatum is the form used in the literature, including the bottlenecking pharmacokinetic critique (resveratrol's first-pass metabolism is aggressive — typical serum levels are 1–10% of the dose). Pterostilbene is the dimethylated analog with markedly higher oral bioavailability and is sometimes preferred as the SIRT1 activator in stack protocols. Used in Resveratrol 600mg, Pterostilbene 100mg, and the NMN+Resveratrol Longevity Stack.

Senolytic flavonoids — Fisetin, Quercetin, Apigenin

Senolytics are agents that selectively kill senescent cells, the metabolically-active but cell-cycle-arrested cells that accumulate with age and drive inflammaging via SASP (senescence-associated secretory phenotype). The leading clinical candidates are: Fisetin — Yousefzadeh 2018 (EBioMedicine, mouse model identifying fisetin as the most-effective senolytic among 10 flavonoids screened) and the Mayo AFFIRM trials (NCT03675724 frailty cohort, NCT04210986 osteoarthritis cohort) at 20 mg/kg human-equivalent doses. Quercetin — paired with the chemotherapy agent dasatinib in the Hickson 2019 D+Q clinical trial; quercetin alone is studied for inflammaging endpoints (Hickson 2019, Justice 2019). Apigenin — CD38 inhibitor (Escande 2013), which is mechanistically interesting because CD38 is the principal NAD+-degrading enzyme that rises with age (Camacho-Pereira 2016 Cell Metab) — apigenin reduces NAD+ degradation in addition to having senolytic activity. Used in Fisetin 500mg, Quercetin 500mg, and Apigenin 50mg + BioPerine; full Senolytics collection.

Mitochondrial actives — CoQ10, PQQ, Urolithin A, ALA

The mitochondrial actives split into two operational groups: biogenesis (making more mitochondria) and mitophagy / quality control (clearing damaged mitochondria so the surviving population is healthier). CoQ10 (Q-SYMBIO trial, Mortensen 2014, n=420 heart-failure 2-year trial — 43% reduction in major adverse cardiac events) is the electron-transport-chain cofactor that declines markedly with age. PQQ (Chowanadisai 2010) supports mitochondrial biogenesis via PGC-1α. Urolithin A (Andreux 2019 Nat Metab, Singh 2022 AMAZ-02) activates PINK1/Parkin-mediated mitophagy. Alpha-lipoic acid (Ziegler 2011 NATHAN1, n=460 4-year diabetic neuropathy) is a universal antioxidant + mitochondrial cofactor. Used in CoQ10 400mg, PQQ 20mg, Urolithin A 500mg, Alpha-Lipoic Acid 600mg, and the Mitochondrial Renewal collection.

Methyl donors and cofactors — TMG, Glycine, Apigenin

NAD+ precursor protocols draw down the body's methyl-donor pool because nicotinamide (a downstream product of NAD+ catabolism) is methylated for excretion as 1-methyl-nicotinamide, consuming SAMe (S-adenosyl-methionine) as the methyl-group donor. Stacking a methyl donor — TMG (trimethylglycine, three methyl groups), glycine, or methylfolate — replenishes the pool. Apigenin's CD38-inhibition role also reduces NAD+ → nicotinamide flux, which by mass-balance reduces methylation demand. Used in TMG 1000mg, Glycine 1500mg, Apigenin 50mg.

Glutathione precursors and antioxidants — NAC, Glycine, Glutathione, ALA, Vitamin C, Astaxanthin

The glutathione cycle is the master cytosolic antioxidant system. The substrate for glutathione synthesis is the GlyNAC pairing (Glycine + N-Acetyl-Cysteine — Sekhar 2021 Nutrients, Kumar 2022 Aging Cell) which raises intracellular glutathione, with downstream effects on insulin sensitivity, oxidative stress markers, and gait speed. We carry both halves separately for users who want to titrate, plus reduced glutathione directly, plus ALA (which recycles oxidized glutathione back to its reduced form), plus liposomal vitamin C (the obligate co-antioxidant), plus natural astaxanthin (the membrane-spanning carotenoid antioxidant). Browse Antioxidants collection.

Foundational micronutrients — D3, K2, Magnesium, Omega-3, Taurine, Creatine

Before any longevity-protocol layer makes sense, baseline micronutrient status has to be addressed. The literature here is unsexy but high-evidence: VITAL (Manson 2019 NEJM, n=25,871) for D3 and Omega-3; Knapen 2015 (Thromb Haemost, n=244, 3-year arterial-stiffness reduction) for K2 MK-7; PURE (Leong 2015 Lancet) on grip-strength mortality (which is partly a creatine and protein-floor question); REDUCE-IT (Bhatt 2019 NEJM, n=8,179) for high-EPA Omega-3 cardiovascular reduction; Singh/Bhasin 2023 (Science) for taurine deficiency as an aging biomarker; Forbes 2022 (Adv Nutr meta) for creatine + sarcopenia. Used across D3 + K2 MK-7, Magnesium Glycinate 400mg, Omega-3 Fish Oil 2000mg, Taurine 1000mg, Creatine 1000mg, and the Foundational Health collection.

Skin, beauty, and connective tissue — Marine Collagen, Multi-Collagen, Hyaluronic Acid, Biotin, Liposomal C, Astaxanthin

Oral collagen peptides at ≤3 kDa molecular weight raise serum hydroxyproline and skin elasticity / dermal density (Proksch 2014 Skin Pharmacol Physiol; Choi 2014; Asserin 2015). Low-MW hyaluronic acid (Oe 2017 J Sci Food Agric) raises skin moisture content. Liposomal vitamin C (Pullar 2017 Nutrients) supports collagen synthesis as the rate-limiting cofactor for prolyl-4-hydroxylase. Astaxanthin (Tominaga 2017) reduces UVA-induced skin damage. Used across Marine Collagen 5000mg, Multi-Collagen Complex 5-Type Capsules, Multi-Collagen Powder, HA + Vitamin C, Biotin 10,000 mcg, Liposomal Vitamin C 1000mg, Astaxanthin 12mg, Beauty Stack; full Collagen collection, Beauty & Anti-Aging, Skin Protocol.

Adaptogens, metabolic, epigenetic — KSM-66, Berberine, CaAKG, Spermidine, Curcumin

KSM-66 ashwagandha (Chandrasekhar 2012, n=64, 27.9% cortisol reduction) for HPA-axis and stress endpoints. Berberine HCl (Yin 2008, Lan 2015 27-RCT meta-analysis) for AMPK activation, glucose, and lipid endpoints. Calcium α-ketoglutarate (Asadi Shahmirzadi 2020, TruDiagnostic 2021) for the alpha-KG / methylation / DNA-demethylation pathway. Spermidine (Eisenberg 2016 Nat Med, Schroeder 2021 SmartAge) for autophagy. Curcumin (Sahebkar 2014 meta, Derosa 2016) for inflammation. Used in KSM-66 600mg, Berberine HCl 500mg, CaAKG 1000mg, Spermidine 10mg, Curcumin 1000mg + BioPerine; full Metabolic collection, Cardiovascular Longevity, Brain & Cognitive Longevity, Fertility collection.

Capsules, excipients, and bottle materials

The capsule and bottle around an active ingredient is the part nobody markets, and is also the part that determines whether the active is shelf-stable enough to actually deliver the dose on the label by the time you take it.

Capsule shells

• HPMC (hydroxypropyl methylcellulose) vegetarian capsules. Cellulose-derived, vegan-suitable, no animal product. Used for the majority of our capsule actives — NMN, NR, Resveratrol, Pterostilbene, Quercetin, Fisetin, Apigenin, Curcumin, CaAKG, Berberine, KSM-66, NAC, Glycine, TMG, Spermidine, Urolithin A, ALA, PQQ, Multi-Collagen Capsules. HPMC capsules are non-animal and avoid the gelatin-source (BSE / vegan) concerns that historically attached to gelatin softgels.
• Bovine gelatin softgels. Used only where the active is a lipid-based liquid that needs softgel encapsulation for stability — Omega-3 Fish Oil, Vitamin D3 + K2 MK-7, Astaxanthin (oil-suspended), Biotin (suspended in MCT). The gelatin source is grass-fed bovine (US/EU origin). The gelatin is BSE-region-screened; we do not use Chinese-supply-chain gelatin.
• Stick-pack and powder formats. Liquid NAD+ is delivered as flavored stick packs; Multi-Collagen Powder is delivered loose in a sealed pouch with a scoop. Powder products use the same bottle / pouch / desiccant approach as the capsule products — opaque packaging, foil seal, desiccant, batch / best-by code printed on the pouch.

Excipients (the small things that aren't the active)

• Microcrystalline cellulose. A neutral plant-fiber bulking agent used to bring capsule fill weight up to a uniform target. Inert, non-allergenic.
• Magnesium stearate (where used). Flow agent for encapsulation machinery. Used in trace amounts (typically <1% of capsule mass) where mechanical processing requires it. The "magnesium stearate is dangerous" claim in some corners of the supplement internet is not supported by the toxicology literature; we use it sparingly because we don't need much, not because of toxicity concerns.
• Silicon dioxide (silica). Anti-caking agent for powder products and some capsules. Inert.
• What we don't use as excipients. No artificial colors, no titanium dioxide (banned in the EU as a food additive since 2022 over genotoxicity concerns), no FD&C dyes, no shellac coatings, no carrageenan, no maltodextrin in capsule fills, no soy lecithin in non-liposomal products.

Bottle materials and packaging

• Opaque amber HDPE bottles for capsule and softgel products. HDPE is BPA-free, food-grade plastic; the amber color blocks UV light that would degrade light-sensitive actives (resveratrol, astaxanthin, K2 MK-7, omega-3).
• Foil induction seal under the cap. Tamper-evidence on the unopened bottle. If the seal is not intact when you open the bottle, do not take the product — contact us for a replacement.
• Silica desiccant packet inside the bottle. Moisture control extends shelf life. The packet is "Do Not Eat" labeled (per industry convention); leave it in the bottle until the bottle is empty.
• Cotton fill (where used). Some capsule bottles include a cotton fill at the top to prevent capsule breakage during shipping. Discard the cotton on opening.
• Outer carton (selected products). Stack bundles and gift configurations ship in an outer carton; routine single-bottle orders ship in a padded mailer or a small carton depending on order configuration.

What's not in our products

The shorter list is what we deliberately leave out — across the entire catalog, by formulation policy, not by accident.

• No artificial colors (no FD&C dyes, no Red 40 / Yellow 5 / Blue 1).
• No titanium dioxide. Banned in the EU as a food additive since 2022 over EFSA genotoxicity concerns; we excluded it from our supply chain as soon as the EFSA opinion was published.
• No carrageenan. Inflammatory in some animal models; we use less-controversial alternatives (gum acacia, microcrystalline cellulose) where a thickener is needed.
• No maltodextrin in capsule fills. High glycemic index for an inert filler is unnecessary; microcrystalline cellulose does the same job.
• No proprietary blends. See NAD+ 5-in-1 supplement-facts panel for the worked example of how a multi-active is itemized.
• No "Made with" claims that disguise sub-doses. If the dose is too small to do what the literature says it does, the active doesn't go on the label, period.
• No "natural flavors" hiding allergens. Liquid NAD+ stick packs disclose flavor source (e.g., natural berry flavor from genuine fruit-derived flavor compounds, not a generic "natural flavor" mask).
• No shellac coatings, no glycerin oversprays. Capsule fills only.
• No GMO source ingredients in plant-extract actives — wheat-germ Spermidine is non-GMO wheat, Soy Lecithin (where used) is non-GMO, BioPerine and KSM-66 are non-GMO.
• No prescription pharmaceuticals masquerading as supplements. No rapamycin, no metformin, no dasatinib, no GHK-Cu peptide, no BPC-157, no lithium orotate as a "longevity" supplement, no semaglutide. These are prescription drugs with prescription-drug evidence requirements; we don't carry them and we don't speak about them as if they were supplements.
• No "stem cell activation" or "telomerase activator" claims with weak evidence. No TA-65 (single-supplier, methodologically thin trial base). No epitalon. No "exosome" supplements (orally-bioavailable exosomes are not a thing).
• No allergens hidden in capsule excipients. Most capsule fills are HPMC (vegan); the few softgels are bovine gelatin (disclosed); collagen products are wild-caught fish, grass-fed bovine, US-source eggshell, and chicken (disclosed by name on each product page).

Storage and stability — practical guidance for your bottle

Stability of the active depends on temperature, moisture, and (for some molecules) light. Here's the practical version.

• Room temperature, dry, dark. Default for all capsule and softgel products. A kitchen or bathroom cabinet works as long as humidity stays in normal range. Do not store on a sunny windowsill.
• Refrigeration (optional). The most heat- and light-sensitive actives — Liquid NAD+ stick packs, NMN powder, NR — benefit from refrigerator storage after opening. Refrigeration extends shelf life beyond the printed best-by date by ~3–6 months in our internal stability testing.
• Avoid the bathroom in humid climates. If you live somewhere with high ambient humidity, the bathroom (with a hot shower nearby) is a worse storage location than a dry kitchen cabinet. The desiccant inside the bottle helps but isn't infinite.
• Don't transfer to a pill organizer for more than 1–2 weeks at a time. Pill organizers expose the active to ambient moisture and light during the daily-dosing routine. This is fine for a week but not for a month.
• Best-by date is conservative. "Best by" is the date by which the active is guaranteed to be at ≥90% label claim. After that date, the active gradually degrades — for most molecules, you'd expect >80% potency a year past best-by, and >70% potency two years past. The bottle isn't unsafe past best-by; the dose is just slowly drifting downward.
• Don't take a supplement whose seal is broken or whose contents look or smell wrong. Capsules should be intact; powders should flow freely; softgels shouldn't leak or be stuck together. If anything looks wrong, contact us for a replacement (see our 30-day guarantee).

How to verify your specific batch

You don't have to take our word for any of this. Here's exactly how to verify the bottle in your hand.

1. Find the batch lot number on your bottle. Bottom panel or back panel; typically a 5–8-character alphanumeric code (e.g., "L23-A0431"), printed alongside the best-by date.
2. Email support@truehealthprotocol.health with that batch lot, the product name, the best-by date, and (optional) your order number. See the per-batch CoA email-flow section above for the four-field email format.
3. Receive the lab PDF within one business day. The PDF will be the original, unmodified, lab letterhead with batch lot, dates, methods, results, and signatory.
4. Read the CoA against the label claim. The "How to read a CoA" section above tells you what each field means and what to look for.
5. Optional: verify the lab's ISO/IEC 17025 accreditation. The accreditation number on the CoA can be looked up on the accrediting body's public registry — A2LA (USA) for many of our domestic CoAs, UKAS or DAkkS for European CoAs. This is a one-minute web check.
6. If anything looks wrong, ask. Email us with the specific question. If a result is on the higher end of a Prop 65 limit (still passing — the limits are conservative), we'll explain what the number means and why the batch passes the standard. If you'd like the underlying chromatography or a re-test, we'll route the request through QC.

Industry shortcuts to recognize on other labels

You don't have to be a chemist to spot most of the supplement industry's worst label tricks. Here are the patterns that come up over and over.

Trick 1 — The proprietary blend

"Memory Boost Blend, 800 mg" with six ingredients listed and no individual amounts. The headline-active is almost always under-dosed; the cheapest filler ingredient is almost always the bulk of the blend. Look for individual milligram amounts on every active. (We addressed this in the "Why we don't use proprietary blends" section above.)

Trick 2 — The wrong form

"Magnesium 400 mg" without specifying form — most often this is magnesium oxide, which is poorly absorbed (~4% bioavailability) and is the form behind the "magnesium causes loose stools" reputation. Look for "magnesium bisglycinate" / "magnesium glycinate" / "magnesium citrate" / "magnesium malate" on the label. Same logic: "K2" without "MK-7" specification (often MK-4, which has a 1–2-hour half-life vs. MK-7's 72 hours); "vitamin D" without "D3" (D2 is less effective at raising serum 25-OH-D); "omega-3" without "TG-form" (ethyl-ester forms have ~70% lower absorption); "resveratrol" without "trans-" (cis-resveratrol is biologically inactive).

Trick 3 — The sub-clinical dose

Bottle says "Berberine, 50 mg per capsule" with a serving size of 6 capsules to reach 300 mg — so you have to take six capsules to reach a dose that's still below the clinical-trial range (1500 mg/day in the Yin 2008 and Lan 2015 trials). Look for actual milligram doses that match the published trial doses. Our Berberine 500mg delivers a clinical-trial-aligned dose at 1–3 capsules/day.

Trick 4 — The "third-party tested" claim with no evidence

"Third-party tested!" printed on the bottle, with no accreditation number, no batch-by-batch CoA workflow, no specifics. Ask: who is the third-party lab, and can I see the CoA for the bottle in my hand? If the answer is "we don't share CoAs" or "we tested once in 2019," the claim is theatrical.

Trick 5 — Unnamed sourcing

"Premium NMN" or "high-quality KSM-66 spec" — without naming the actual supplier or the actual standardization. Ask: which manufacturer? Which spec? Which trial-grade reference, if any? Brands that name their suppliers (Selerb, Ixoreal Biomed for KSM-66, Sabinsa for BioPerine, Albion/Balchem for TRAACS, AlzChem for Creapure) are accountable to the trial supply chain. Brands that don't, aren't.

Trick 6 — Amazon resale and counterfeit risk

Even legitimate brands lose control of their supply chain on Amazon: the FBA "commingled inventory" model means that bottles from many sellers go into a shared pool and the bottle you receive may not have come from the brand directly. The Labdoor / Consumer Reports 2022–2023 investigations documented counterfeit and incorrectly-stored bottles in the Amazon supplement supply chain at non-trivial rates. We sell direct only — through truehealthprotocol.health — so the supply chain from manufacturer → warehouse → your door is end-to-end accountable.

Trick 7 — "Doctor formulated" with no doctor named

"Formulated by a longevity doctor!" with no actual doctor named. Ask: which doctor? What credentials? What's their formulation rationale published anywhere? A formulation lineage you can verify is qualitatively different from a marketing tagline.

Trick 8 — Front-panel claims with no clinical-trial support

"Reverses biological age!" / "Adds 10 years to your life!" / "Cures fatigue!" These are unsupported by any published trial and (with respect to disease-treatment language) are also not permitted on a dietary supplement label per FDA structure-function-claim rules (21 CFR 101.93). Look for measured language tied to specific endpoints: "supports healthy NAD+ levels," "supports cellular energy metabolism," "supports cardiovascular function" — these are the legally-permitted forms of structure-function claims, and they are an honest framing of what supplements actually do.

What we're still working on

We aim to be transparent about gaps as well as strengths. The current state of the catalog is good, not yet complete. Active workstreams as of this revision:

• Public CoA portal. Right now CoAs are by email request; we're scoping a customer-portal lookup that ties batch lot to CoA PDF without the email round-trip. Engineering complexity is moderate (it requires a customer-account-aware document-store integration and a way to handle the long tail of batches across the catalog). Target: H2 2026.
• Subscription / auto-ship. Currently most products ship as one-time orders; a subscription tier with rate-locked pricing for repeat customers is in design. Target: Q3 2026.
• Expanded NAD+ family. NMN-equivalent dosed Liposomal-NMN (vs. our current NR-direct liposomal); β-NAD oral with established stability profile.
• Broader fertility-support catalog. Currently Fertility is anchored by CoQ10 + foundationals; the literature supports a broader fertility stack (myo-inositol, NAC, alpha-lipoic acid, omega-3, vitamin D3, methylated B-complex). The CoQ10 400mg page lists the relevant fertility trial citations (Bentov 2010, Showell 2017 Cochrane).
• GlyNAC pre-formulated combination product. Currently NAC 600mg + Glycine 1500mg are sold separately for users who want to titrate; a 1:2 (NAC:Glycine) combination product matching Sekhar 2021 ratios is in formulation review.
• Senolytic-pulse calendar. The literature suggests pulse-dosing senolytics (a few days on, weeks off) rather than continuous daily dosing — but the optimal schedule is still being characterized. We're building a calendar tool to help customers track pulse-protocols across Fisetin and Quercetin stacks.
• Direct-to-consumer biomarker integration. Linking the Our Science biomarker layer (CBC/CMP/ApoB/HbA1c, methylation clocks, functional measures) to product recommendations through a partnership with a third-party lab is in scoping. Target: 2026.

FAQ — quality and sourcing

Where are the products manufactured?

The contract-manufacturing locations split between FDA-registered, FDA-inspected facilities in the United States (the majority of capsule and softgel actives) and cGMP-certified facilities in the European Union (selected actives where the EU supply chain is the longer-established one — Spermidine wheat-germ extract, polyphenol-grade Apigenin, certain TG-form Omega-3 batches, Liposomal NAD+). Each product page names the relevant manufacturing partner where there is a named branded supplier (Selerb, KSM-66 / Ixoreal Biomed, BioPerine / Sabinsa, TRAACS / Albion-Balchem, Creapure / AlzChem). See the "Named manufacturing partners" section above.

Are products tested by a real third-party lab or by the manufacturer?

Both — but the document we send you on request is the third-party lab's CoA. Tier 1 of our verification workflow is in-house QC at the contract manufacturer; Tier 2 is the ISO/IEC 17025-accredited third-party lab (Eurofins, SGS, Alkemist, or equivalent); Tier 3 is the lot-release reviewer comparing Tier 1 and Tier 2 numbers. The bottle only ships if all three pass. See "The three-tier verification standard" section above.

Can I see the CoA before I buy?

Yes. Email support@truehealthprotocol.health with the product name and we'll send a representative recent batch CoA (it won't be your specific bottle's CoA — your bottle hasn't shipped yet — but it will be a real CoA from a real recent batch of the product you're researching). Once you order and have the bottle in hand, you can request the specific CoA tied to your batch lot.

Are the products non-GMO?

Plant-extract actives are non-GMO (wheat-germ Spermidine is non-GMO wheat; KSM-66 is non-GMO ashwagandha; Berberis aristata for Berberine is non-GMO). For products with carriers — soy lecithin in Liposomal NAD+, sunflower lecithin in Liposomal Vitamin C — we use non-GMO carriers wherever the supply chain offers them. Capsule materials (HPMC) and excipients (microcrystalline cellulose, magnesium stearate, silica) are non-GMO by nature of being plant-cellulose and inorganic-mineral inputs.

Are the products gluten-free?

The actives are gluten-free with one explicit exception: Spermidine wheat-germ extract. Spermidine is extracted from wheat germ, and while the extraction process removes the bulk of wheat protein (including gluten), the product is not certified gluten-free. We label the Spermidine 10mg product clearly as wheat-germ-derived. If you have celiac disease or are managing non-celiac gluten sensitivity at the strict level, do not take Spermidine — use a non-wheat senolytic stack of Fisetin + Quercetin + Apigenin instead.

Are the products vegan?

It depends on the product. HPMC capsule products are vegan. Softgel products (Omega-3, Vitamin D3 + K2 MK-7, Astaxanthin, Biotin) currently use bovine gelatin and are not vegan. Marine Collagen is fish-derived. Multi-Collagen Complex contains chicken and bovine collagen. Eggshell-membrane products are not vegan. Each product page has the vegan/vegetarian status in the description.

What if a batch fails testing?

It doesn't ship. The batch is held by QC, the deviation is investigated, and the affected raw materials are quarantined. Failures are rare in our supply chain because we use suppliers with their own incoming-material testing, but the workflow exists. In catalog history, two batches have been rejected at lot-release; both were re-manufactured and the re-manufactured batches passed all three tiers.

What if I receive a bottle whose seal is broken?

Don't take it. Contact us and we'll replace the bottle and arrange return of the broken-seal one. Tampered or damaged bottles are an integrity issue and we'd rather replace than have you take a chance. See the 30-day guarantee for the full damaged / lost / wrong-product workflow.

Do you sell direct or through Amazon?

Direct only at this time. Buying through any channel that isn't truehealthprotocol.health means we can't guarantee the bottle's storage history or that it isn't a counterfeit. The Amazon supplement counterfeit problem is well-documented (Labdoor / Consumer Reports 2022–2023 investigations); until we control the warehousing layer, we'd rather customers buy direct.

What is the difference between cGMP, FDA-registered, and FDA-approved?

These are distinct — and the distinction matters. cGMP-certified means the facility follows current Good Manufacturing Practice standards for dietary supplements (21 CFR Part 111). FDA-registered means the facility has filed Form FDA 3537 establishing itself as a manufacturer of dietary supplements (a paperwork registration). FDA-inspected means an FDA investigator has physically inspected the facility under 21 CFR Part 111 since the last registration cycle. FDA-approved is what prescription drugs are; dietary supplements are not "FDA-approved" because they don't undergo the New Drug Application (NDA) approval process. Any supplement brand claiming "FDA approved" is misrepresenting the regulatory framework.

What does ISO/IEC 17025 mean?

ISO/IEC 17025 is the international standard for testing and calibration laboratories. An ISO/IEC 17025-accredited lab has demonstrated technical competence for the specific test methods listed on its scope of accreditation. The accreditation is granted by a recognized accrediting body (A2LA in the US, UKAS in the UK, DAkkS in Germany, COFRAC in France) and is verifiable on the accrediting body's public registry. Our CoAs come from ISO/IEC 17025-accredited labs for the specific methods used (HPLC for identity / potency, ICP-MS for heavy metals, USP <2021>/<2022> for microbial, GC-MS / LC-MS for pesticides).

What is California Proposition 65 and why does it matter for supplements?

Cal Prop 65 (officially the Safe Drinking Water and Toxic Enforcement Act of 1986) requires businesses selling products in California to warn consumers about exposure to listed chemicals — including the four heavy metals (lead, cadmium, arsenic, mercury) at exposure levels above the Safe Harbor limits. The Safe Harbor limits are: lead ≤ 0.5 µg/day, cadmium ≤ 4.1 µg/day, inorganic arsenic ≤ 10 µg/day, inorganic mercury ≤ 0.3 µg/day, methyl mercury ≤ 0.7 µg/day. These are stricter than the USP <232> oral PDE limits, which is why we test against the Prop 65 ceiling specifically — if a batch passes Prop 65, it passes all major heavy-metal standards globally.

What is the ±10% potency tolerance?

USP and FDA recognize that the true active-ingredient content of a finished dosage form will vary from batch to batch within an analytically-determined tolerance — typically ±10% of label claim. A label says "500 mg per capsule"; the assay may come back as "503 mg" or "486 mg," both of which are within tolerance and are reported on the CoA. Most of our batches come in tighter than ±10% (typically ±3–5%); we've never released a batch outside ±10%.

What is the difference between USP <232> and ICH Q3D?

Both are analytical-standards documents for elemental impurities (the technical term for heavy metals plus a few other elements). USP <232> is the United States Pharmacopeia chapter; ICH Q3D is the International Council for Harmonisation guideline that USP <232> is harmonized with. The PDE (permitted daily exposure) limits in the two documents are the same. Our CoAs cite whichever method the lab uses; the underlying limits are equivalent.

What is the difference between TAMC and TYMC?

TAMC (Total Aerobic Microbial Count) measures total aerobic bacteria per gram. TYMC (Total Yeast and Mold Count) measures yeast and mold per gram. Both are part of USP <2021> / <2022> microbial testing and both are reported on a CoA. Limits are method-dependent: typical specifications for capsule products are TAMC ≤ 10³ CFU/g, TYMC ≤ 10² CFU/g, with absence of pathogens (Salmonella, E. coli, S. aureus, P. aeruginosa).

How do I tell if NMN is the β-anomer or the α-anomer?

You can't tell from the bottle, but you can verify from the CoA. The β/α anomer ratio is reported on every batch CoA for NMN products in our catalog (typical ratio is ≥98% β / ≤2% α). The α-anomer is a manufacturing impurity with markedly lower bioactivity; well-made NMN material has minimal α content. If a brand can't or won't disclose the β/α ratio, that's a yellow flag for the batch quality.

How do I tell if my Resveratrol or Pterostilbene is the trans-isomer?

Trans-isomer status is verified on the CoA. The HPLC chromatogram shows the trans-peak (the bioactive form) and (where present) the cis-peak (the inactive isomerization byproduct). For our material, the trans-isomer ratio is ≥98% on every batch.

What is "patented" or "patent-protected" for supplement ingredients?

Supplement-ingredient patents are typically composition-of-matter or process patents covering a specific manufacturing method, extract specification, or formulation. KSM-66, BioPerine, TRAACS, Creapure, Niagen, Mitopure are all examples of patent-protected ingredients with specific spec attached to the patent. The patent does not mean the ingredient is more bioactive than alternatives by definition — but it does mean the spec is consistent batch-to-batch and traceable to a single accountable supplier, which is the operational value.

Do you do allergen testing?

Allergen-testing is method-dependent and is run per-product per-allergen. The collagen products (marine, multi-collagen, eggshell-membrane) are allergen-tested for the relevant allergens. The capsule actives are run on dedicated production lines that exclude major allergens (peanut, tree nut, soy, wheat, dairy, egg, fish, shellfish) for the capsule fill — except in cases where the active itself is the allergen (e.g., Spermidine wheat-germ extract — clearly labeled), or where the softgel format requires fish-oil active (Omega-3 — clearly labeled).

Do you test for glyphosate (Roundup) residue?

Yes — for plant-extract actives sourced from supply chains where glyphosate exposure is a documented concern (any agricultural-source plant extract). The pesticide-residue panel includes glyphosate-specific testing (LC-MS/MS) where the supply chain warrants it. Wheat-germ Spermidine specifically is glyphosate-tested on every batch.

Do you test for melamine?

Melamine is a non-issue for our actives because we don't source plant-protein or pet-food-adjacent ingredients (the historical melamine adulteration cases were in protein-content fortification of milk, infant formula, and pet food). We do not source any active from supply chains where melamine adulteration has been a documented concern, and our incoming-material identity testing would catch melamine adulteration of any nitrogen-content-spoofed actives if it were present.

What about radiation testing for marine collagen and fish oil?

Marine-source ingredients (Marine Collagen, Omega-3, Astaxanthin) are sourced from supply chains with documented radiation-monitoring protocols post-Fukushima. The Omega-3 supply chain is anchored in Peru / North Atlantic anchovy and sardine; Marine Collagen is wild-caught from Atlantic / Pacific (specific origin per batch); Astaxanthin is microalgae-derived (Hawaii or Iceland), not fish-derived. Radiation panels (cesium-137, strontium-90 where relevant) are run per supplier qualification rather than per batch, but documentation is on file.

Where can I get the most up-to-date version of this page?

This page is the source of truth, and is updated whenever a sourcing or testing process changes. The "How we revise this page" section below shows the explicit revision history.

What if I have a question about a specific batch that isn't covered above?

Email support@truehealthprotocol.health with the product, batch lot, and your specific question. Every email is answered by a human within one business day. Specific batch questions are routed to QC if needed.

Selected primary references

The references below are anchor citations for the analytical-standards, manufacturing-spec, and clinical-evidence claims made on this page. The full per-active citation list lives on Our Science and on each individual product page.

Analytical and regulatory standards

• 21 CFR Part 111 — Current Good Manufacturing Practice in Manufacturing, Packaging, Labeling, or Holding Operations for Dietary Supplements (FDA, 2007).
• 21 CFR 101.36 — Nutrition labeling of dietary supplements (FDA).
• 21 CFR 101.93 — Certain types of statements for dietary supplements (FDA, structure-function-claim rules).
• USP <232> — Elemental Impurities — Limits (United States Pharmacopeia).
• USP <233> — Elemental Impurities — Procedures (United States Pharmacopeia).
• USP <2021> — Microbial enumeration tests, nutritional and dietary supplements.
• USP <2022> — Microbiological procedures for absence of specified microorganisms, nutritional and dietary supplements.
• USP <467> — Residual Solvents.
• USP <701> — Disintegration.
• ICH Q3D — Guideline for Elemental Impurities (International Council for Harmonisation).
• ISO/IEC 17025 — General requirements for the competence of testing and calibration laboratories.
• California Proposition 65 — Safe Drinking Water and Toxic Enforcement Act of 1986 (Office of Environmental Health Hazard Assessment, OEHHA Safe Harbor levels).
• EU MRL — Regulation (EC) No 396/2005 on maximum residue levels of pesticides in or on food and feed of plant and animal origin.
• EFSA Scientific Opinion (2021) — Safety assessment of titanium dioxide (E 171) as a food additive (basis for the EU 2022 ban).

Clinical-evidence anchors for the catalog

• Yoshino M, et al. (2021). Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science.
• Yamaguchi S, et al. (2022). Safety and efficacy of long-term (12-week) oral nicotinamide mononucleotide. Endocrine Journal.
• Trammell SAJ, et al. (2016). Nicotinamide riboside is uniquely and orally bioavailable in mice and humans. Nature Communications.
• Brakedal B, et al. (2022). The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease. Cell Metabolism.
• Howitz KT, et al. (2003). Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature.
• Hubbard BP, Sinclair DA. (2013). Small molecule SIRT1 activators for the treatment of aging and age-related diseases. Trends in Pharmacological Sciences.
• Yousefzadeh MJ, et al. (2018). Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine.
• Mayo AFFIRM trials — NCT03675724 (Mayo Clinic frailty cohort), NCT04210986 (osteoarthritis cohort).
• Andreux PA, et al. (2019). The mitophagy activator urolithin A is safe and induces a molecular signature of improved mitochondrial and cellular health in humans. Nature Metabolism.
• Asadi Shahmirzadi A, et al. (2020). Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice. Cell Metabolism.
• Eisenberg T, et al. (2016). Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature Medicine.
• Sekhar RV. (2021). GlyNAC supplementation improves glutathione deficiency, oxidative stress, mitochondrial dysfunction, inflammation, aging hallmarks, metabolic defects, muscle strength, cognitive decline, and body composition: implications for healthy aging. Journal of Nutrition.
• Mortensen SA, et al. (2014). The effect of coenzyme Q10 on morbidity and mortality in chronic heart failure: results from Q-SYMBIO. JACC: Heart Failure.
• Ziegler D, et al. (2011). Efficacy and safety of antioxidant treatment with α-lipoic acid over 4 years in diabetic polyneuropathy: the NATHAN 1 trial. Diabetes Care.
• Lan J, et al. (2015). Meta-analysis of the effect and safety of berberine in the treatment of type 2 diabetes mellitus, hyperlipidemia, and hypertension. Journal of Ethnopharmacology.
• Yin J, et al. (2008). Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism.
• Knapen MHJ, et al. (2015). Menaquinone-7 supplementation improves arterial stiffness in healthy postmenopausal women. Thrombosis and Haemostasis.
• Manson JE, et al. (2019). Vitamin D supplements and prevention of cancer and cardiovascular disease (VITAL). New England Journal of Medicine.
• Bhatt DL, et al. (2019). Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia (REDUCE-IT). New England Journal of Medicine.
• Chandrasekhar K, et al. (2012). A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian Journal of Psychological Medicine.
• Shoba G, et al. (1998). Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers. Planta Medica.
• Singh P, et al. (2023). Taurine deficiency as a driver of aging. Science (Singh / Bhasin).
• Forbes SC, et al. (2022). Effects of creatine supplementation on properties of muscle, bone, and brain function in older adults: a narrative review. Journal of Dietary Supplements.
• Proksch E, et al. (2014). Oral supplementation of specific collagen peptides has beneficial effects on human skin physiology. Skin Pharmacology and Physiology.
• Oe M, et al. (2017). Oral hyaluronan relieves knee pain: a review. Nutrition Journal.
• Pullar JM, et al. (2017). The roles of vitamin C in skin health. Nutrients.
• Camacho-Pereira J, et al. (2016). CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metabolism.
• Dyerberg J, et al. (2010). Bioavailability of marine n-3 fatty acid formulations. Prostaglandins, Leukotrienes and Essential Fatty Acids.
• López-Otín C, et al. (2013, 2023). The hallmarks of aging. Cell (twelve-hallmark 2023 update).
• Horvath S. (2013). DNA methylation age of human tissues and cell types. Genome Biology.
• Belsky DW, et al. (2022). DunedinPACE, a DNA methylation biomarker of the pace of aging. eLife.

How we revise this page

This page is the source of truth on True Health Protocol's quality, sourcing, manufacturing, and testing workflows. We revise it whenever a sourcing process changes, a manufacturing partner is added, a testing method is updated, or a customer question reveals a gap in coverage.

• 2026-05 update. Major flagship rewrite. Added 60-second answer block, on-page table of contents, three-tier verification operational detail, named manufacturing partners section (Selerb, KSM-66 / Ixoreal Biomed, BioPerine / Sabinsa, TRAACS / Albion-Balchem, Creapure / AlzChem), country-of-origin transparency table for all 33 actives, bioavailable-form checklist, deeper sourcing-by-family section, capsule / excipient / bottle-material detail, "what's not in our products" exclusion list, storage-stability practical guidance, batch-verification step-by-step flow, 8-pattern industry-shortcut recognition guide, what-we're-still-working-on transparency block, FAQ expansion (was 9 entries, now 21), 30+ analytical-standards and clinical-evidence references, 91-link related-pages sitemap. Fixed support email (was the founder's personal email, now support@truehealthprotocol.health, consistent with the rest of the catalog). SEO meta refreshed for the expanded scope.
• 2026-Q1 prior version. Original Quality & Sourcing page covering five-line summary, label policy, third-party testing description, manufacturing standards, ingredient-family sourcing, FAQ. The current page expands every one of those sections with operational detail, citations, and catalog cross-links.
• Anticipated 2026-H2 updates. Customer-portal CoA lookup (target Q3 2026), expanded Fertility-stack catalog (myo-inositol, NAC, ALA), GlyNAC pre-formulated combination product, senolytic-pulse calendar tool, biomarker-integration partnership.

Related pages

This page is one node in a larger network covering the why, the how, the what, and the after-purchase of every product in the catalog. The full sitemap of related pages and product crosslinks:

Reading order — for new customers

1. About True Health Protocol — the founder narrative, the brand commitments, why the catalog exists.
2. Our Science — the Hallmarks of Aging framework that organizes the catalog.
3. How It Works — what to expect from First Order to Month 6.
4. Getting Started — where to begin if you're new to longevity supplementation.
5. Protocols — supplement stacks organized by goal.
6. Ingredient Sourcing — the deep per-active sourcing detail (this page is the operational summary).
7. Quality & Sourcing — this page.
8. FAQ — frequently-asked customer questions.
9. Our 30-Day Guarantee — the operational refund policy with edge cases.
10. Contact — how to reach support, including the per-batch CoA email flow described above.
11. Business registration disclosure — entity registration information.

Policies (formal-language versions)

• Privacy Policy
• Refund Policy (mirror of /pages/guarantee in formal-policy language)
• Shipping Policy
• Terms of Service
• Your Privacy Choices (CCPA opt-out)

Browse the catalog by Hallmark / goal / onboarding tier

• All Products — the full catalog
• Most Popular
• Starter Bundles
• Longevity Essentials
• Top Picks
• Foundational Health
• NAD+ Family · NMN sub-collection
• Senolytics
• Mitochondrial Renewal
• Antioxidants
• Cardiovascular Longevity
• Brain & Cognitive Longevity
• Metabolic
• Fertility
• Collagen Supplements
• Beauty & Anti-Aging
• Skin Protocol

Every active SKU referenced on this page

NAD+: NMN 1000mg · Pure NMN 500mg · NR Hard Capsules · Liquid NAD+ · Liposomal NAD+ 1000mg · NAD+ Daily Boost · NAD+ Pure Focus 1000mg · NAD+ 5-in-1 Mitochondrial.

Sirtuin / methyl: Resveratrol 600mg · Pterostilbene 100mg · TMG 1000mg · NMN+Resveratrol Stack.

Senolytic: Fisetin 500mg · Quercetin 500mg · Apigenin 50mg + BioPerine.

Mitochondrial: CoQ10 400mg · PQQ 20mg · Urolithin A 500mg · Alpha-Lipoic Acid 600mg.

Antioxidant / glutathione: NAC 600mg · Glycine 1500mg · Glutathione 500mg · Liposomal Vitamin C 1000mg · Astaxanthin 12mg.

Foundational: D3 + K2 MK-7 · Magnesium Glycinate 400mg · Omega-3 2000mg · Taurine 1000mg · Creatine 1000mg.

Adaptogen / metabolic / epigenetic: KSM-66 Ashwagandha 600mg · Berberine HCl 500mg · CaAKG 1000mg · Spermidine 10mg · Curcumin 1000mg + BioPerine.

Skin / beauty: Marine Collagen 5000mg · Multi-Collagen Complex 5-Type Capsules · Multi-Collagen Powder 1lb · HA + Vitamin C · Biotin 10,000 mcg · Beauty Stack.

Our standard, in one sentence

If we wouldn't take it ourselves at the dose printed on the label, we don't sell it. That's the bar — full milligram doses, named ingredients with named manufacturing partners, three-tier verification with ISO/IEC 17025-accredited third-party testing, manufactured in cGMP-certified FDA-registered facilities, batch-code traceable, and free of the labeling tricks the rest of the supplement industry routinely uses. The supplement industry has a low average. We're aiming above it.

Read more in Our Science, our 30-day guarantee, the Ingredient Sourcing page, the FAQ, and About True Health Protocol. Questions about a specific product or batch? Email support@truehealthprotocol.health — every email is answered by a human within one business day.

FDA disclaimer. These statements have not been evaluated by the Food and Drug Administration. The products discussed on this page are not intended to diagnose, treat, cure, or prevent any disease. Speak with a qualified healthcare provider before starting any supplement, especially if you are pregnant, nursing, taking a prescription medication, or managing a medical condition. Active-ingredient potency, heavy-metal levels, and microbial counts vary within published specifications batch-to-batch — the per-batch CoA is the operational truth for the bottle in your hand.